Metaxalone
Active ingredient
- Drug class
- -
- Availability
- Prescription only
- Routes
- Oral
- Markets covered
- 1
- Products on record
- 4
- FDA reports (12 mo)
- 92
Overview
Plain-language summary, compiled from the cited regulatory records
Metaxalone is a medication used to relieve discomfort associated with acute, painful musculoskeletal conditions [1]. It is intended for use as an adjunct to rest, physical therapy, and other measures [1]. The exact way metaxalone works is not fully understood, but it may be linked to its sedative effects [1]. It is important to note that metaxalone does not directly relax tense skeletal muscles in humans [1].
This medication is available under various brand names [N]. In the past 12 months, there have been 92 adverse event reports associated with metaxalone [2]. Among the frequently reported adverse events are nausea, vomiting, off-label use, arthralgia (joint pain), and back pain [2].
This is not medical advice. Consult a qualified healthcare professional.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| US United States | FDA | 4 | January 20, 2025 |
USUnited States· FDA
4 products
Uses
INDICATIONS AND USAGE
Metaxalone is indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomforts associated with acute, painful musculoskeletal conditions. The mode of action of this drug has not been clearly identified, but may be related to its sedative properties.
Metaxalone does not directly relax tense skeletal muscles in man.
How to take
Drug interactions
Known interactions involving Metaxalone. Select one for details. This list is informational and not a complete interaction checker.
Showing 240 of 246. Type above to find a specific drug.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]FDA DailyMed · 02c42f72-5d78-43… · revised July 25, 2022 [PDF]
- [2]OpenFDA adverse-event reports (US), 12 months ending June 4, 2026.
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.