Loperamide
Antipropulsives
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- Drug class
- Antipropulsives
- Availability
- Prescription and OTC
- Routes
- Oral
- Markets covered
- 3
- Products on record
- 76
Overview
Plain-language summary, compiled from the cited regulatory records
Loperamide is an active pharmaceutical ingredient classified as an antidiarrheal agent [1]. It functions by slowing down the movement of the intestines, which helps to reduce the frequency of bowel movements [1].
Loperamide is approved for controlling symptoms associated with diarrhea. This includes the management of travelers' diarrhea [1]. It is available under various brand names [1].
The number of adverse event reports for loperamide submitted within a 12-month period is not specified in the provided data [2].
This is not medical advice. Consult a qualified healthcare professional.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| GB United Kingdom | MHRA | 70 | May 29, 2026 |
| US United States | FDA | 5 | May 28, 2026 |
| CA Canada | Health Canada | 1 | March 22, 2025 |
GBUnited Kingdom· MHRA
70 products
Uses
For the symptomatic treatment of acute diarrhoea in adults and children aged 12 years and over. For the symptomatic treatment of acute episodes of diarrhoea associated with Irritable Bowel Syndrome in adults aged 18 years and over following initial diagnosis by a doctor.
How to take
USUnited States· FDA
5 products
Uses
Use controls symptoms of diarrhea, including Travelers' Diarrhea
How to take
CACanada· Health Canada
1 product
Uses
AND CLINICAL USE..................................................................................... 3 CONTRAINDICATIONS ....................................................................................................... 4 WARNINGS AND PRECAUTIONS.......................................................................................
4 ADVERSE REACTIONS ...................................................................................................... 14 PART II: SCIENTIFIC INFORMATION ..............................................................................
25 PART III: CONSUMER INFORMATION............................................................................ 29 Page 3 of 31 LOPERAMIDE loperamide hydrochloride tablets USP 2 mg PART I: HEALTH PROFESSIONAL INFORMATION SUMMARY PRODUCT INFORMATION Route of Administration Dosage Form / Strength All Nonmedicinal Ingredients Oral Caplet/2 mg D&C yellow #10, FD&C blue #1, lactose, magnesium stearate, microcrystalline cellulose and starch.
Drug interactions
Known interactions involving Loperamide. Select one for details. This list is informational and not a complete interaction checker.
Showing 240 of 573. Type above to find a specific drug.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]MHRA (UK) · PL282780103 · revised December 29, 2025
- [2]FDA DailyMed · 01efdce1-25ce-45… · revised January 11, 2024 [PDF]
- [3]Health Canada (DPD) · 02377764 · revised March 22, 2025
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.