Liothyronine

Liothyronine is indicated in adults and children for the treatment of coma of myxedema, the management of severe chronic thyroid deficiency and hypothyroid states occurring in the treatment of thyrotoxicosis. Liothyronine sodium can be used also as an adjunct to carbimazole to prevent subclinical hypothyroidism developing during carbimazole treatment of thyrotoxicosis.

Liothyronine sodium may be preferred for treating severe and acute hypothyroid states because of its rapid and more potent effect, but thyroxine sodium is normally the drug of choice for routine replacement therapy.

AND CLINICAL USES

Cytomel® is indicated in conditions of inadequate endogenous thyroid production. These: include: a.

HYPOTHYROIDISM:

As replacement or supplemental therapy in patients with hypothyroidism of any etiology except transient hypothyroidism during the recovery phase of subacute thyroiditis b.

SIMPLE (non-toxic) GOITER:

Cytomel® may be tried therapeutically in an attempt to reduce the size of such a goiter, the rationale being that suppression of pituitary thyroid stimulating hormone (TSH) removes at least one of the growth-promoting factors. Cytomel® may be used in the T3 suppression test to differentiate suspected hyperthyroidism from euthyroidism.

(See special instructions under ADMINISTRATION AND DOSAGE), Cytomel® can be used in patients allergic to dessicated thyroid or thyroid extract derived from pork or beef.

3 ) Limitations of Use : - Not indicated for suppression of benign thyroid nodules and nontoxic diffuse goiter in iodine-sufficient patients. ( 1 ) - Not indicated for treatment of hypothyroidism during the recovery phase of subacute thyroiditis.

1 Hypothyroidism Liothyronine sodium tablets are indicated as a replacement therapy in primary (thyroidal), secondary (pituitary), and tertiary (hypothalamic) congenital or acquired hypothyroidism. 2 Pituitary Thyrotropin (Thyroid-Stimulating Hormone, TSH) Suppression Liothyronine sodium tablets are indicated as an adjunct to surgery and radioiodine therapy in the management of well-differentiated thyroid cancer .

3 Thyroid Suppression Test Liothyronine sodium tablets are indicated as a diagnostic agent in suppression tests to differentiate suspected mild hyperthyroidism or thyroid gland autonomy. 4) ] . Liothyronine sodium tablets are not indicated for treatment of hypothyroidism during the recovery phase of subacute thyroiditis.