Ketoprofen
Active ingredient · 2 therapeutic classes
- Drug class
- Propionic Acid Derivatives
- Availability
- Prescription only
- Routes
- Oral
- Markets covered
- 3
- Products on record
- 15
- FDA reports (12 mo)
- 1,197
Overview
Plain-language summary, compiled from the cited regulatory records
Ketoprofen is a medication belonging to the drug class of propionic acid derivatives [1]. It is approved for managing the signs and symptoms of rheumatoid arthritis and osteoarthritis [1].
When considering ketoprofen extended-release capsules, it is important to carefully weigh the potential benefits against the risks [1]. The lowest effective dose should be used for the shortest duration necessary to achieve individual patient treatment goals [1]. Ketoprofen extended-release capsules are not recommended for certain uses [1].
In the past 12 months, there have been 1197 adverse event reports associated with ketoprofen [2]. The most frequently reported reactions include infusion site pain, headache, off-label use, pain, and infusion site erythema [2].
This is not medical advice. Consult a qualified healthcare professional.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| GB United Kingdom | MHRA | 11 | May 15, 2026 |
| CA Canada | Health Canada | 3 | March 22, 2025 |
| US United States | FDA | 1 | July 15, 2024 |
GBUnited Kingdom· MHRA
11 products
Uses
Tiloket CR Capsules are indicated for: • Rheumatoid arthritis • Osteoarthritis • Ankylosing spondylitis • Acute articular and periarticular disorders (bursitis, capsulitis, synovitis, tendonitis) • Cervical spondylitis • Low back pain (strain, lumbago, sciatica, fibrositis) • Painful musculoskeletal conditions • Dysmenorrhoea.
How to take
CACanada· Health Canada
3 products
Uses
KETOPROFEN, KETOPROFEN-E and KETOPROFEN SR (Ketoprofen Capsules BP, Ketoprofen Enteric-coated Tablets and Ketoprofen Sustained-release Tablets) are indicated for: the treatment of the signs and symptoms of rheumatoid arthritis, osteoarthritis, the treatment of primary dysmenorrhea, the relief of mild to moderate acute pain associated with musculotendinous trauma (sprains and strains), postoperative (including dental surgery) or postpartum pain.
For patients with an increased risk of developing CV and/or GI adverse events, other management strategies that do NOT include the use of NSAIDs should be considered first (see
How to take
USUnited States· FDA
1 product
Uses
INDICATIONS AND USAGE
Carefully consider the potential benefits and risks of ketoprofen extended-release capsules before deciding to use ketoprofen extended-release capsules. Use the lowest effective dose for the shortest duration consistent with individual patient treatment goals (see WARNINGS ).
Ketoprofen extended-release capsules are indicated for the management of the signs and symptoms of rheumatoid arthritis and osteoarthritis. Ketoprofen extended-release capsules are not recommended for treatment of acute pain because of its extended-release characteristics (see CLINICAL PHARMACOLOGY: Pharmacokinetics ).
How to take
Drug interactions
Known interactions involving Ketoprofen. Select one for details. This list is informational and not a complete interaction checker.
Showing 240 of 439. Type above to find a specific drug.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]MHRA (UK) · PL113110103 · revised March 7, 2022
- [2]Health Canada (DPD) · 00790435 · revised March 22, 2025
- [3]FDA DailyMed · 198a4140-f4c0-44… · revised July 15, 2024 [PDF]
- [4]OpenFDA adverse-event reports (US), 12 months ending June 4, 2026.
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.