Hydroflumethiazide: Uses, Side Effects, Dosage - Drugvu

ℹ️ Compiled from public regulatory records · Last regulator revision: October 3, 2025🚩 Report this page

Hydroflumethiazide

Thiazides, Plain

GB MHRA

Drug class: Thiazides, Plain
Availability: See label
Markets covered: 1
Products on record: 1

Overview

Hydroflumethiazide is an active pharmaceutical ingredient in the Thiazides, Plain group (C03AA). The information below is compiled per regulator from the product labels on record, with direct links to the original documents.

Regulatory status by market

Market	Regulator	Products	Last revision
GB United Kingdom	MHRA	1	October 3, 2025

GBUnited Kingdom· MHRA

1 product

Uses

GBOfficial regulatory label· revised October 3, 2025[1]

NEO-URIZIDE is a diuretic used to reduce oedema of cardiac, renal or hepatic origin; also other types of oedema including iatrogenic oedema. It is also used in pre-menstrual tension. NEO-URIZIDE is useful in the treatment of hypertension either alone or with a hypotensive agent.

How to take

Drug interactions

Known interactions involving Hydroflumethiazide. Select one for details. This list is informational and not a complete interaction checker.

Aminolevulinic Acid Amiodarone Arsenic Trioxide Cisapride Dofetilide Dolasetron Dronedarone Droperidol Lithium Carbonate Pimozide Tizanidine Ziprasidone Acarbose Acebutolol Acetohexamide Albiglutide Albuterol Aldesleukin Alfentanil Alfuzosin Allopurinol Alogliptin Alprazolam Amifostine Amisulpride Amitriptyline Amoxapine Amphotericin B Apomorphine Apraclonidine Arformoterol Aripiprazole Asenapine Atenolol Atracurium Avanafil Baclofen Benazepril Benzhydrocodone Betamethasone Betaxolol Bisacodyl Bisoprolol Brexpiprazole Brimonidine Bromfenac Bumetanide Buprenorphine Bupropion Buspirone Butabarbital Butorphanol Cabergoline Calcifediol Calcitriol Calcium Acetate Calcium Carbonate Calcium Chloride Calcium Citrate Calcium Gluconate Calcium Glycerophosphate Calcium Lactate Calcium Phosphate Canagliflozin Capecitabine Captopril Carbamazepine Cariprazine Carisoprodol Carteolol Carvedilol Castor Oil Celecoxib Chlordiazepoxide Chlorpromazine Chlorpropamide Cholecalciferol Cisatracurium Citalopram Clobazam Clomipramine Clonazepam Clorazepate Clozapine Codeine Colestipol Corticotropin Cosyntropin Cyclophosphamide Cyclosporine Dapagliflozin Deflazacort Deserpidine Desvenlafaxine Dexamethasone Dexlansoprazole Dexmedetomidine Dexmethylphenidate Diatrizoate Diazepam Diazoxide Diclofenac Diflunisal Digitoxin Digoxin Dihydrocodeine Dihydrotachysterol Disopyramide Doxacurium Doxazosin Doxepin Doxercalciferol Dronabinol Dulaglutide Duloxetine Empagliflozin Enalapril Epoprostenol Ergocalciferol Ertugliflozin Escitalopram Eslicarbazepine Esomeprazole Ethacrynate Ethanol Etodolac Exenatide Fenoldopam Fenoprofen Fentanyl Fludrocortisone Fluorouracil Fluoxetine Fluphenazine Flurazepam Flurbiprofen Fluvoxamine Formoterol Fosinopril Furosemide Glimepiride Glipizide Glyburide Glycerin Guanabenz Guanadrel Guanethidine Guanfacine Haloperidol Hydrocodone Hydrocortisone Hydromorphone Hydroxyzine Ibuprofen Iloperidone Iloprost Imipramine Indacaterol Indomethacin Insulin Degludec Insulin Detemir Insulin Glargine Insulin Lispro Iodipamide Iodixanol Iohexol Iopamidol Iopromide Iothalamic Acid Ioversol Ioxilan Irinotecan Isocarboxazid Isoetharine Ketoprofen Ketorolac Labetalol Lactitol Lactulose Lansoprazole Levobunolol Levodopa Levomilnacipran Licorice Linagliptin Linezolid Liraglutide Lisinopril Lixisenatide Lofexidine Lorazepam Loxapine Lumateperone Lurasidone Magnesium Citrate Magnesium Hydroxide Maprotiline Maraviroc Meclofenamic Acid Mefenamate Meloxicam Meperidine Meprobamate Mesoridazine Metaproterenol Metformin Methadone Methdilazine Methenamine Methocarbamol Methotrexate Methotrimeprazine Methoxsalen Methylphenidate Methylprednisolone Metipranolol Metocurine Metoprolol Midazolam Miglitol Milnacipran Mineral Oil Mirtazapine Mivacurium Moexipril Molindone Morphine Nabilone Nabumetone Nadolol Nalbuphine Naproxen Nateglinide Nebivolol Nefazodone Olanzapine Oliceridine Olodaterol Olopatadine Omeprazole

Showing 240 of 372. Type above to find a specific drug.

Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.

Sources & citations

[1]MHRA (UK) · PL334140048 · revised October 3, 2025

Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.

Side effects & warnings

GBOfficial regulatory label· Adverse reactions· revised October 3, 2025[1]

Impotence. Mild anorexia or indigestion may be avoided by taking dose after meals. The following have also been reported as undesirable effects of thiazide diuretics: postural hypotension, hypokalaemia, hyponatraemia, hypomagnesaemia, hypercalcaemia, hypochloraemic alkalosis, gout, hyperuricaemia, hyperglycaemia, altered plasma lipid concentrations, skin rashes, photosensitivity, blood disorders (including neutropenia and thrombocytopenia), hypersensitivity reactions, pancreatitis, intrahepatic cholestasis, bone marrow depression.
Cases of choroidal effusion with visual field defect have been reported after the use of thiazide and thiazide-like diuretics. Gastrointestinal disorders, not known (frequency cannot be estimated from the available data): diarrhoea

GBOfficial regulatory label· Warnings and precautions· revised October 3, 2025[1]

NEO-URIZIDE may precipitate or aggravate diabetes and may impair control of diabetes in patients receiving sulphonylureas. Supplementary potassium is strongly recommended in patients receiving digitalis who require prolonged diuretic treatment.
May cause hypokalaemia, which may be corrected with potassium or a potassium- sparing drug. Renal function should be monitored. Increased risk of hypomagnesaemia in alcoholic cirrhosis. May aggravate gout. Serum uric acid levels may be raised with or without gout in some patients.
Treat with caution in hepatic or renal impairment (avoid if severe). May aggravate systemic lupus erythematosus. Blood dyscrasias and pancreatitis have been reported. Patients on long-term treatment and elderly patients need blood tests to monitor blood electrolyte levels and blood dyscrasias.
Expectant mothers who receive thiazide diuretics may be at increased risk from acute haemorrhagic pancreatitis; thrombocytopenia has been reported in newborn infants following antepartum use of thiazides. Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine.
Choroidal effusion, acute myopia and secondary angle-closure glaucoma:
Sulfonamide or sulfonamide derivative drugs can cause an idiosyncratic reaction resulting in choroidal effusion with visual field defect, transient myopia and acute angle-closure glaucoma. Symptoms include acute onset of decreased visual acuity or ocular pain and typically occur within hours to weeks of drug initiation.
Untreated acute angle-closure glaucoma can lead to permanent vision loss, the primary treatment is to discontinue drug intake as rapidly as possible. Prompt medical or surgical treatments may need to be considered if the intraocular pressure remains uncontrolled.
Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy.

This is not medical advice. Consult a qualified healthcare professional.

Overview

Regulatory status by market

GBUnited Kingdom· MHRA

Drug interactions

Drugs in the same class

Sources & citations