Histamine
Active ingredient
Sold as SOLUPRICK POSITIVE AND…
- Drug class
- -
- Availability
- Prescription only
- Routes
- Percutaneous, Intradermal
- Markets covered
- 3
- Products on record
- 4
Overview
Histamine is an active pharmaceutical ingredient. The information below is compiled per regulator from the product labels on record, with direct links to the original documents.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| GB United Kingdom | MHRA | 2 | April 10, 2026 |
| US United States | FDA | 1 | August 28, 2020 |
| CA Canada | Health Canada | 1 | July 11, 2025 |
GBUnited Kingdom· MHRA
2 products
Uses
This medicinal product is for diagnostic use only. Positive and negative control of skin-prick tests for diagnosis of specific IgE- mediated allergy.
How to take
USUnited States· FDA
1 product
Uses
INDICATIONS AND USAGE
For use as a positive control in evaluation of allergenic (immediate hypersensitivity or "Type I") skin testing.
How to take
CACanada· Health Canada
1 product
Uses
AND CLINICAL USE
Positive Skin Test Control – Histamine is indicated as an adjunct in allergy skin test for diagnosis, as a positive control to test wheal-flare response of skin for evaluation of skin test response to allergenic extracts. CONTRAINDICATIONS Positive Skin Test Control – Histamine is contraindicated in patients with a history of hypersensitivity to histamine products, and in patients with hypotension, severe hypertension, vasomotor instability, severe cardiac, pulmonary or renal disease.
WARNINGS:
Attacks of severe asthma or other serious allergic conditions may be precipitated by the administration of Histamine Dihydrochloride in patients with bronchial disease. Caution is advised in using histamine in such patients and in those with a history of bronchial asthma.
Histamine Dihydrochloride has not been approved for unlabeled use as gastric acid stimulus or for detecting bronchial hyperactivity.
Drug interactions
Known interactions involving Histamine. Select one for details. This list is informational and not a complete interaction checker.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]MHRA (UK) · PL100850019 · revised October 3, 2025
- [2]FDA DailyMed · 1159c24c-d9ce-49… · revised August 28, 2020 [PDF]
- [3]Health Canada (DPD) · 02439514 · revised July 11, 2025
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.