Felodipine

Hypertension Stable angina pectoris

PLENDIL (felodipine) is indicated for: • the treatment of mild to moderate essential hypertension. The combination of PLENDIL with a thiazide diuretic or a beta-blocker has been found to be compatible and showed an additive antihypertensive effect.

The safety and efficacy of concurrent use of PLENDIL with other antihypertensive agents have not been established. 1 Pediatrics Pediatrics (≤ 18 years of age): No data are available to Health Canada; therefore, Health Canada has not authorized an indication for pediatric use.

INDICATIONS AND USAGE

Felodipine extended-release tablets, USP are indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure lowers the risk of fatal and non-fatal cardiovascular events, primarily strokes and myocardial infarctions.

These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including felodipine. Control of high blood pressure should be part of comprehensive cardiovascular risk management, including, as appropriate, lipid control, diabetes management, antithrombotic therapy, smoking cessation, exercise, and limited sodium intake.

Many patients will require more than 1 drug to achieve blood pressure goals. For specific advice on goals and management, see published guidelines, such as those of the National High Blood Pressure Education Program’s Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC).