ℹ️ Compiled from public regulatory records · Last regulator revision: May 15, 2026

Droperidol

Butyrophenone Derivatives

GB MHRAUS FDA

Drug class: Butyrophenone Derivatives
Availability: Prescription only
Routes: Intramuscular, Intravenous
Markets covered: 2
Products on record: 3
FDA reports (12 mo): 102

N05ADButyrophenone Derivatives

Overview

Plain-language summary, compiled from the cited regulatory records

Droperidol is a medication belonging to the butyrophenone derivative class of drugs [1]. It is approved for use in reducing the incidence of nausea and vomiting that can occur with surgical and diagnostic procedures [1].

In the past 12 months, there have been 102 adverse event reports associated with droperidol [2]. Common adverse events reported include acute kidney injury, anuria, constipation, hepatic cytolysis, and urinary retention [2].

Droperidol is available under various brand names [1].

This is not medical advice. Consult a qualified healthcare professional.

Regulatory status by market

Market	Regulator	Products	Last revision
GB United Kingdom	MHRA	2	May 15, 2026
US United States	FDA	1	March 20, 2023

GBUnited Kingdom· MHRA

2 products

Uses

GBOfficial regulatory label· revised May 15, 2026[1]

Prevention and treatment of post-operative nausea and vomiting (PONV) in adults and, as second line, in children (2 to 11 years) and adolescents (12 to 18 years). Prevention of nausea and vomiting induced by morphine and derivatives during post- operative patient controlled analgesia (PCA) in adults.
4.

How to take

USUnited States· FDA

1 product

Uses

USOfficial regulatory label· revised March 20, 2023[2]

INDICATIONS AND USAGE
Droperidol Injection is indicated to reduce the incidence of nausea and vomiting associated with surgical and diagnostic procedures.

How to take

Drug interactions

Known interactions involving Droperidol. Select one for details. This list is informational and not a complete interaction checker.

Abarelix Abiraterone Acetazolamide Adenosine Alfentanil Alfuzosin Alprazolam Amiodarone Amisulpride Amitriptyline Amoxapine Amphotericin B Anagrelide Apalutamide Apomorphine Arsenic Trioxide Asenapine Astemizole Atomoxetine Azithromycin Bedaquiline Bendroflumethiazide Benzthiazide Bepridil Bicalutamide Bosutinib Bumetanide Buprenorphine Butorphanol Cabozantinib Capreomycin Ceritinib Chlordiazepoxide Chloroquine Chlorothiazide Chlorpromazine Chlorthalidone Cilostazol Ciprofloxacin Cisapride Cisplatin Citalopram Clarithromycin Clobazam Clofazimine Clomipramine Clonazepam Clorazepate Clozapine Codeine Crizotinib Dasatinib Daunorubicin Degarelix Desflurane Desipramine Deutetrabenazine Dezocine Diazepam Disopyramide Dofetilide Dolasetron Doxepin Doxorubicin Dronedarone Efavirenz Encorafenib Enflurane Entrectinib Enzalutamide Epirubicin Eribulin Erythromycin Escitalopram Estazolam Ethacrynate Ethanol Ezogabine Fenoldopam Fentanyl Fingolimod Flecainide Fluconazole Fludrocortisone Fluoxetine Fluphenazine Flurazepam Flutamide Foscarnet Fostemsavir Furosemide Gatifloxacin Gemifloxacin Gilteritinib Glasdegib Goserelin Granisetron Grepafloxacin Halazepam Halofantrine Haloperidol Halothane Histrelin Hydrochlorothiazide Hydrocortisone Hydroflumethiazide Hydromorphone Hydroxychloroquine Hydroxyzine Ibutilide Idarubicin Iloperidone Imipramine Indapamide Inotuzumab Ozogamicin Isocarboxazid Isoflurane Isoproterenol Ivabradine Ivosidenib Ketoconazole Lapatinib Lefamulin Lenvatinib Leuprolide Levofloxacin Levorphanol Lisdexamfetamine Lithium Carbonate Lofexidine Lomefloxacin Lopinavir Lorazepam Lumefantrine Macimorelin Mannitol Maprotiline Mefloquine Meperidine Mesoridazine Metaproterenol Methadone Methazolamide Methotrimeprazine Methoxyflurane Metoclopramide Metolazone Mexiletine Midazolam Midostaurin Mifepristone Mirtazapine Morphine Moxifloxacin Nalbuphine Nalmefene Naloxone Naltrexone Nilotinib Nilutamide Norfloxacin Nortriptyline Ofloxacin Oliceridine Ondansetron Osilodrostat Osimertinib Oxaliplatin Oxazepam Oxymorphone Oxytocin Ozanimod Paliperidone Palonosetron Panitumumab Panobinostat Papaverine Pasireotide Patiromer Pazopanib Pentamidine Perflutren Perphenazine Phenelzine Picosulfurate Pimavanserin Pimozide Pitolisant Polythiazide Posaconazole Primaquine Probucol Procainamide Prochlorperazine Promazine Promethazine Propafenone Propoxyphene Protriptyline Quazepam Quetiapine Quinidine Quinine Ranolazine Relugolix Remifentanil Remimazolam Ribociclib Rilpivirine Risperidone Ritodrine Romidepsin Rucaparib Saquinavir Selegiline Selpercatinib Sertraline Sevoflurane Siponimod Sodium Sulfate Solifenacin Sorafenib Sotalol Sparfloxacin Sunitinib Tacrolimus Tamoxifen Telavancin Telithromycin Temazepam Terbutaline Terfenadine Tetrabenazine Thioridazine Tizanidine Toremifene Torsemide Tramadol Tranylcypromine Trazodone

Showing 240 of 493. Type above to find a specific drug.

Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.

Sources & citations

[1]MHRA (UK) · PL154130072 · revised May 15, 2026
[2]FDA DailyMed · 147e033d-d997-4e… · revised March 20, 2023 [PDF]
[3]OpenFDA adverse-event reports (US), 12 months ending June 4, 2026.

Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.