Disulfiram
Active ingredient · 2 therapeutic classes
- Drug class
- Drugs Used In Alcohol Dependence
- Availability
- Prescription only
- Routes
- Oral
- Markets covered
- 2
- Products on record
- 5
- FDA reports (12 mo)
- 107
Overview
Plain-language summary, compiled from the cited regulatory records
Disulfiram is a medication classified as a drug used in alcohol dependence [1]. It is approved as an aid in the management of selected chronic alcohol patients who desire to maintain enforced sobriety. This allows for the application of supportive and psychotherapeutic treatments to their best advantage [1].
Disulfiram is not considered a cure for alcoholism. When administered without adequate patient motivation and supportive therapy, it is unlikely to significantly alter the drinking patterns of individuals with chronic alcoholism [1].
In the past 12 months, there have been 107 adverse event reports associated with disulfiram [2]. Among the frequently reported adverse events are drug-induced liver injury, hypotonia neonatal, neonatal respiratory distress, premature baby, and drug ineffective [2].
This is not medical advice. Consult a qualified healthcare professional.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| GB United Kingdom | MHRA | 4 | May 15, 2026 |
| US United States | FDA | 1 | October 5, 2023 |
GBUnited Kingdom· MHRA
4 products
Uses
Alcohol deterrent compound. Disulfiram may be indicated as an adjuvant in the treatment of carefully selected and co-operative patients with drinking problems. Its use must be accompanied by appropriate supportive treatment.
How to take
USUnited States· FDA
1 product
Uses
INDICATIONS AND USAGE
Disulfiram is an aid in the management of selected chronic alcohol patients who want to remain in a state of enforced sobriety so that supportive and psychotherapeutic treatment may be applied to best advantage. Disulfiram is not a cure for alcoholism.
When used alone, without proper motivation and supportive therapy, it is unlikely that it will have any substantive effect on the drinking pattern of the chronic alcoholic.
How to take
Drug interactions
Known interactions involving Disulfiram. Select one for details. This list is informational and not a complete interaction checker.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]MHRA (UK) · PL002892558 · revised May 1, 2026
- [2]FDA DailyMed · 07abe950-3565-41… · revised October 5, 2023 [PDF]
- [3]OpenFDA adverse-event reports (US), 12 months ending June 4, 2026.
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.