Disopyramide
Antiarrhythmics, Class Ia
Sold as RYTHMODAN
- Drug class
- Antiarrhythmics, Class Ia
- Availability
- Prescription only
- Routes
- Oral
- Markets covered
- 3
- Products on record
- 12
Overview
Disopyramide is an active pharmaceutical ingredient in the Antiarrhythmics, Class Ia group (C01BA). The information below is compiled per regulator from the product labels on record, with direct links to the original documents.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| GB United Kingdom | MHRA | 10 | May 15, 2026 |
| US United States | FDA | 1 | September 25, 2024 |
| CA Canada | Health Canada | 1 | July 2, 2025 |
GBUnited Kingdom· MHRA
10 products
Uses
Properties:
Prevention and control of a wide variety of cardiac arrhythmias, probably by slowing conduction in the his-Purkinje system and by increasing the effective refractory period of the atria and ventricles. Indications: 1. Maintenance of normal rhythm following conversion by parenteral drugs or electroconversion.
2. Prevention of arrhythmias after myocardial infarction. 3. Treatment of persistent ventricular and atrial extrasystoles, paroxysmal supra ventricular tachycardia, Wolff-Parkinson-White syndrome. 4. Suppression of arrhythmias during surgical procedures.
5. Control of arrhythmias following the use of digitalis or similar glycosides.
How to take
USUnited States· FDA
1 product
Uses
INDICATIONS AND USAGE
Disopyramide phosphate is indicated for the treatment of documented ventricular arrhythmias such as sustained ventricular tachycardia, that, in the judgment of the physician, are life-threatening. Because of the proarrhythmic effects of disopyramide phosphate, its use with lesser arrhythmias is generally not recommended.
Treatment of patients with asymptomatic ventricular premature contractions should be avoided. Initiation of disopyramide phosphate treatment, as with other antiarrhythmic agents used to treat life-threatening arrhythmias, should be carried out in the hospital.
Antiarrhythmic drugs have not been shown to enhance survival in patients with ventricular arrhythmias.
CACanada· Health Canada
1 product
Uses
AND CLINICAL USE ...................................................................................... 4 4 CONTRAINDICATIONS ...........................................................................................................
4 5 WARNINGS ................................................................................................................................ 5 6 PRECAUTIONS ..........................................................................................................................
8 7 ADVERSE REACTIONS.......................................................................................................... 12 8 SYMPTOMS AND TREATMENT OF OVERDOSAGE ........................................................ 14 9 DOSAGE AND ADMINISTRATION ......................................................................................
15 10 PHARMACEUTICAL INFORMATION ................................................................................ 16 11 AVAILABILITY OF DOSAGE FORMS ............................................................................... 16 12 PHARMACOLOGY ................................................................................................................
Drug interactions
Known interactions involving Disopyramide. Select one for details. This list is informational and not a complete interaction checker.
Showing 240 of 509. Type above to find a specific drug.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]MHRA (UK) · PL450430030 · revised March 13, 2026
- [2]FDA DailyMed · 11a68e26-d2e4-48… · revised September 25, 2024 [PDF]
- [3]Health Canada (DPD) · 02224801 · revised July 2, 2025
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.