Dimethyl Sulfoxide
Active ingredient · 2 therapeutic classes
Sold as RIMSO-50
- Drug class
- Other Urologicals
- Availability
- See label
- Routes
- Intravesical
- Markets covered
- 1
- Products on record
- 1
Overview
Dimethyl Sulfoxide is an active pharmaceutical ingredient in the Other Urologicals group (G04BX). The information below is compiled per regulator from the product labels on record, with direct links to the original documents.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| CA Canada | Health Canada | 1 | March 22, 2025 |
CACanada· Health Canada
1 product
Uses
AND CLINICAL USES RIMSO-50 (dimethyl sulfoxide) is indicated for the symptomatic relief of patients with interstitial cystitis. RIMSO-50 has not been approved as being safe and effective for any other indication. There is no clinical evidence of effectiveness of dimethyl sulfoxide in the treatment of bacterial infections of the urinary tract.
CONTRAINDICATIONS None. WARNINGS DIMETHYL SULFOXIDE CAN INITIATE THE LIBERATION OF HISTAMINE AND THERE HAS BEEN AN OCCASIONAL HYPERSENSITIVITY REACTION WITH TOPICAL ADMINISTRATION OF DIMETHYL SULFOXIDE. THIS HYPERSENSITIVITY HAS NOT OCCURRED IN PATIENTS RECEIVING INTRAVESICAL RIMSO-50; HOWEVER, THE PHYSICIAN SHOULD BE COGNIZANT OF THIS POSSIBILITY IN PRESCRIBING RIMSO-50.
IF ANAPHYLACTOID SYMPTOMS DEVELOP, APPROPRIATE THERAPY SHOULD BE INSTITUTED. SOME DATA INDICATES THAT DIMETHYL SULFOXIDE POTENTIATES OTHER CONCOMITANTLY ADMINISTERED MEDICATIONS. PRECAUTIONS Changes in the refractive index and lens opacities have been seen in monkeys, dogs and rats given dimethyl sulfoxide chronically.
Drug interactions
Known interactions involving Dimethyl Sulfoxide. Select one for details. This list is informational and not a complete interaction checker.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]Health Canada (DPD) · 00493392 · revised March 22, 2025
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.