Desloratadine
Other Antihistamines For Systemic Use
Sold as Allex · Aerius · Azomyr · Opulis · Aerinaze
- Drug class
- Other Antihistamines For Systemic Use
- Availability
- Prescription only
- Routes
- Oral
- Markets covered
- 4
- Products on record
- 32
- FDA reports (12 mo)
- 422
Overview
Plain-language summary, compiled from the cited regulatory records
Desloratadine is a medication belonging to the drug class of other antihistamines for systemic use [1]. It is approved to treat symptoms associated with allergic rhinitis, both seasonal and perennial, in individuals 12 years of age and older [1]. Additionally, desloratadine is indicated for the symptomatic relief of chronic idiopathic urticaria, including reducing itching, the number of hives, and the size of hives, also in patients aged 12 and above [1].
In the market, desloratadine is available under various brand names [1]. Adverse event reports for desloratadine within the last 12 months total 422 [2]. The most frequently reported reactions include off-label use, nausea, pruritus, fatigue, and headache [2].
This is not medical advice. Consult a qualified healthcare professional.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| GB United Kingdom | MHRA | 16 | May 15, 2026 |
| EU European Union | EMA | 8 | April 7, 2026 |
| CA Canada | Health Canada | 7 | April 16, 2026 |
| US United States | FDA | 1 | July 10, 2025 |
GBUnited Kingdom· MHRA
16 products
Uses
1)
How to take
EUEuropean Union· EMA
8 products
Uses
Aerinaze is indicated in adults and adolescents 12 years and older for the symptomatic treatment of seasonal allergic rhinitis when accompanied by nasal congestion.
How to take
CACanada· Health Canada
7 products
Uses
1 Pediatrics Pediatrics (<12 years of age): AERIUS® SINUS + ALLERGY is not recommended for use in children below the age of 12 years due to lack of data on safety and efficacy. 2 Geriatrics Geriatrics (≥65 years of age): AERIUS® SINUS + ALLERGY should be used with caution in patients 65 years of age and above.
How to take
USUnited States· FDA
1 product
Uses
1 INDICATIONS AND USAGE Desloratadine Tablets are a histamine-1 (H1) receptor antagonist indicated for: • Seasonal Allergic Rhinitis: relief of nasal and non-nasal symptoms in patients 12 years of age and older. 1 ) • Perennial Allergic Rhinitis: relief of nasal and non-nasal symptoms in patients 12 years of age and older.
2 ) • Chronic Idiopathic Urticaria: symptomatic relief of pruritus, reduction in the number of hives, and size of hives in patients 12 years of age and older. 1 Seasonal Allergic Rhinitis Desloratadine Tablets are indicated for the relief of the nasal and non-nasal symptoms of seasonal allergic rhinitis in patients 12 years of age and older.
2 Perennial Allergic Rhinitis Desloratadine Tablets are indicated for the relief of the nasal and non-nasal symptoms of perennial allergic rhinitis in patients 12 years of age and older. 3 Chronic Idiopathic Urticaria Desloratadine Tablets are indicated for the symptomatic relief of pruritus, reduction in the number of hives, and size of hives, in patients with chronic idiopathic urticaria 12 years of age and older.
Drug interactions
Known interactions involving Desloratadine. Select one for details. This list is informational and not a complete interaction checker.
Showing 240 of 259. Type above to find a specific drug.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]MHRA (UK) · PL204160242 · revised May 15, 2026
- [2]European Medicines Agency · EMEA/H/C/000772 · revised April 7, 2026
- [3]Health Canada (DPD) · 02309300 · revised April 16, 2026
- [4]FDA DailyMed · 0fe374d0-c14b-41… · revised July 10, 2025 [PDF]
- [5]OpenFDA adverse-event reports (US), 12 months ending June 4, 2026.
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.