ℹ️ Compiled from public regulatory records · Last regulator revision: March 6, 2026🚩 Report this page

Dantrolene

Dantrolene and Derivatives

GB MHRAUS FDA

Drug class: Dantrolene and Derivatives
Availability: Prescription only
Routes: Oral
Markets covered: 2
Products on record: 16

Overview

Dantrolene is an active pharmaceutical ingredient in the Dantrolene and Derivatives group (M03CA). The information below is compiled per regulator from the product labels on record, with direct links to the original documents.

Regulatory status by market

Market	Regulator	Products	Last revision
GB United Kingdom	MHRA	15	March 6, 2026
US United States	FDA	1	December 22, 2024

GBUnited Kingdom· MHRA

15 products

Uses

GBOfficial regulatory label· revised October 17, 2025[1]

Dantrium capsules are indicated for the treatment of chronic, severe spasticity of skeletal muscle resulting from disorders such as stroke, spinal cord injury, cerebral palsy and multiple sclerosis in adults and children over the age of 5 years old weighing 25 kg or more.

How to take

USUnited States· FDA

1 product

Uses

USOfficial regulatory label· revised December 22, 2024[2]

INDICATIONS AND USAGE
, spinal cord injury, stroke, cerebral palsy, or multiple sclerosis). It is of particular benefit to the patient whose functional rehabilitation has been retarded by the sequelae of spasticity. Such patients must have presumably reversible spasticity where relief of spasticity will aid in restoring residual function.
Dantrolene sodium is not indicated in the treatment of skeletal muscle spasm resulting from rheumatic disorders. If improvement occurs, it will ordinarily occur within the dosage titration (see DOSAGE AND ADMINISTRATION ), and will be manifested by a decrease in the severity of spasticity and the ability to resume a daily function not quite attainable without dantrolene sodium.
Occasionally, subtle but meaningful improvement in spasticity may occur with dantrolene sodium therapy. In such instances, information regarding improvement should be solicited from the patient and those who are in constant daily contact and attendance with him.

Drug interactions

Known interactions involving Dantrolene. Select one for details. This list is informational and not a complete interaction checker.

Alfentanil Benzhydrocodone Buprenorphine Butorphanol Codeine Dezocine Dienestrol Diethylstilbestrol Dihydrocodeine Estradiol Estrone Ethinyl Estradiol Fentanyl Hydrocodone Hydromorphone Leflunomide Levorphanol Lomitapide Meperidine Mestranol Methadone Mipomersen Morphine Nalbuphine Oliceridine Oxycodone Oxymorphone Pentazocine Pexidartinib Propoxyphene Quinestrol Remifentanil Sufentanil Tapentadol Teriflunomide Tramadol Alprazolam Amitriptyline Amlodipine Amobarbital Amoxapine Apomorphine Apraclonidine Aripiprazole Asenapine Asparaginase Azatadine Baclofen Bedaquiline Biperiden Botulinum Toxin Type A Botulinum Toxin Type B Brentuximab Vedotin Brexanolone Brexpiprazole Brimonidine Brivaracetam Bromocriptine Brompheniramine Buspirone Butabarbital Butalbital Calaspargase Pegol Cannabidiol Carbamazepine Carbinoxamine Cariprazine Carisoprodol Cenobamate Cetirizine Chlordiazepoxide Chlormezanone Chlorpheniramine Chlorpromazine Citalopram Clemastine Clobazam Clofarabine Clomipramine Clonazepam Clorazepate Clozapine Cyclizine Cyproheptadine Desipramine Desvenlafaxine Deutetrabenazine Dexbrompheniramine Dextromethorphan Diazepam Diltiazem Diphenhydramine Doxepin Doxylamine Dronabinol Droperidol Duloxetine Efavirenz Entacapone Epirubicin Escitalopram Esketamine Eslicarbazepine Estazolam Eszopiclone Ethanol Ethosuximide Ethotoin Ezogabine Felbamate Flavoxate Flibanserin Fluoxetine Fluphenazine Flurazepam Fluvoxamine Fosphenytoin Gabapentin Halazepam Haloperidol Hydroxyzine Idelalisib Ifosfamide Iloperidone Imipramine Interferon Beta-1a Interferon Beta-1b Isocarboxazid Ketamine Lamotrigine Lasmiditan Lemborexant Levamlodipine Levetiracetam Levocetirizine Lithium Carbonate Lofexidine Lorazepam Loxapine Lumateperone Lurasidone Maprotiline Mephenytoin Mephobarbital Meprobamate Mesoridazine Metaxalone Methotrexate Methsuximide Metoclopramide Metyrosine Midazolam Mirtazapine Molindone Nabilone Naltrexone Nefazodone Nortriptyline Olanzapine Olopatadine Opicapone Opium Oxazepam Oxcarbazepine Paliperidone Paraldehyde Paramethadione Paroxetine Pegaspargase Peginterferon Beta-1a Pentobarbital Perampanel Pergolide Perphenazine Phenacemide Phenelzine Phenobarbital Phensuximide Phenyltoloxamine Phenytoin Pimozide Pramipexole Pregabalin Primidone Prochlorperazine Procyclidine Promazine Promethazine Propiomazine Protriptyline Pyrilamine Quazepam Quetiapine Ramelteon Rasagiline Remdesivir Remimazolam Risperidone Ropinirole Rotigotine Rufinamide Secobarbital Sertraline Sibutramine Stiripentol Suvorexant Tasimelteon Temazepam Tetrabenazine Thalidomide Thioguanine Thioridazine Thiothixene Tiagabine Tizanidine Tolcapone Topiramate Trabectedin Tranylcypromine Trazodone Triazolam Trifluoperazine Triflupromazine Trihexyphenidyl Trimeprazine Trimethadione Trimethobenzamide Trimipramine Tripelennamine Triprolidine Valbenazine Valproate Vecuronium Venlafaxine Verapamil Vigabatrin Zaleplon Ziconotide Ziprasidone Zolpidem

Showing 240 of 277. Type above to find a specific drug.

Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.

Sources & citations

[1]MHRA (UK) · PL200110033 · revised October 17, 2025
[2]FDA DailyMed · 11689f56-15e0-43… · revised December 22, 2024 [PDF]

Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.