Chlorzoxazone
Oxazol, Thiazine, and Triazine Derivatives
- Drug class
- Oxazol, Thiazine, and Triazine Derivatives
- Availability
- Prescription only
- Routes
- Oral
- Markets covered
- 1
- Products on record
- 3
- FDA reports (12 mo)
- 46
Overview
Plain-language summary, compiled from the cited regulatory records
Chlorzoxazone is a medication belonging to the oxazol, thiazine, and triazine derivatives drug class [1]. It is approved for use as an adjunct to rest, physical therapy, and other measures to relieve discomfort associated with acute, painful musculoskeletal conditions [1]. The exact way chlorzoxazone works is not fully understood, but it may be linked to its sedative effects [1]. It is important to note that chlorzoxazone does not directly relax tense skeletal muscles in humans [1].
In the past 12 months, there have been 46 adverse event reports associated with chlorzoxazone [2]. Common reactions reported include dizziness, nausea, pain, diarrhea, and myalgia [2]. Chlorzoxazone is available under various brand names [1].
This is not medical advice. Consult a qualified healthcare professional.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| US United States | FDA | 3 | March 16, 2025 |
USUnited States· FDA
3 products
Uses
INDICATIONS
Chlorzoxazone is indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomfort associated with acute, painful musculoskeletal conditions. The mode of action of this drug has not been clearly identified, but may be related to its sedative properties.
Chlorzoxazone does not directly relax tense skeletal muscles in man.
How to take
Drug interactions
Known interactions involving Chlorzoxazone. Select one for details. This list is informational and not a complete interaction checker.
Showing 240 of 303. Type above to find a specific drug.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]FDA DailyMed · 0a8ee5fa-f393-45… · revised March 1, 2025 [PDF]
- [2]OpenFDA adverse-event reports (US), 12 months ending June 4, 2026.
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.