ℹ️ Compiled from public regulatory records · Last regulator revision: May 1, 2026🚩 Report this page

Bumetanide

Sulfonamides, Plain

Sold as BURINEX

US FDAGB MHRACA Health Canada

Drug class: Sulfonamides, Plain
Availability: Prescription only
Routes: Oral, Intramuscular, Intravenous
Markets covered: 3
Products on record: 16
FDA reports (12 mo): 1,749

Overview

Bumetanide is an active pharmaceutical ingredient in the Sulfonamides, Plain group (C03CA). The information below is compiled per regulator from the product labels on record, with direct links to the original documents.

Regulatory status by market

Market	Regulator	Products	Last revision
US United States	FDA	9	May 1, 2026
GB United Kingdom	MHRA	5	April 10, 2026
CA Canada	Health Canada	2	April 23, 2026

USUnited States· FDA

9 products

Uses

USOfficial regulatory label· revised January 8, 2025[1]

INDICATIONS AND USAGE
Bumetanide tablets, USP are indicated for the treatment of edema associated with congestive heart failure, hepatic and renal disease, including the nephrotic syndrome. Almost equal diuretic response occurs after oral and parenteral administration of bumetanide.
Therefore, if impaired gastrointestinal absorption is suspected or oral administration is not practical, bumetanide should be given by the intramuscular or intravenous route. Successful treatment with bumetanide tablets, USP following instances of allergic reactions to furosemide suggests a lack of cross-sensitivity.

How to take

GBUnited Kingdom· MHRA

5 products

Uses

GBOfficial regulatory label· revised April 10, 2026[2]

g. congestive heart failure, renal dysfunction including nephrotic syndrome and cirrhosis of the liver in adults. In oedema of renal or cardiac origin where high doses of a potent short - acting diuretic are required, Bumetanide 5 mg may be used in adults.

How to take

CACanada· Health Canada

2 products

2 products on record with this regulator. Detailed label text (uses, dosage, side effects) is being ingested — the original document is linked under Sources [3].

Brands in Canada (1)

BURINEXKARO PHARMA AB

Drug interactions

Known interactions involving Bumetanide. Select one for details. This list is informational and not a complete interaction checker.

Amikacin Aminolevulinic Acid Amiodarone Arsenic Trioxide Cisapride Desmopressin Dofetilide Dolasetron Dronedarone Droperidol Etelcalcetide Gentamicin Kanamycin Lithium Carbonate Neomycin Netilmicin Pimozide Plazomicin Streptomycin Tizanidine Tobramycin Ziprasidone Acarbose Acebutolol Acetohexamide Albiglutide Albuterol Aldesleukin Alendronate Alfentanil Alogliptin Alprazolam Amifostine Amisulpride Amitriptyline Amoxapine Amphotericin B Apomorphine Apraclonidine Arformoterol Aripiprazole Asenapine Atenolol Atracurium Avanafil Baclofen Benazepril Bendroflumethiazide Benzhydrocodone Benzthiazide Betamethasone Betaxolol Bisacodyl Bisoprolol Brexpiprazole Brimonidine Bromfenac Buprenorphine Bupropion Buspirone Butabarbital Butorphanol Cabergoline Canagliflozin Captopril Carbamazepine Carboplatin Cariprazine Carisoprodol Carteolol Carvedilol Castor Oil Cefaclor Cefadroxil Cefamandole Cefazolin Cefdinir Cefditoren Cefepime Cefixime Cefmetazole Cefonicid Cefoperazone Cefotaxime Cefotetan Cefoxitin Cefpodoxime Cefprozil Ceftaroline Fosamil Ceftazidime Ceftibuten Ceftizoxime Ceftolozane Ceftriaxone Cefuroxime Celecoxib Cephalexin Chlordiazepoxide Chlorothiazide Chlorpromazine Chlorpropamide Chlorthalidone Cisatracurium Cisplatin Citalopram Clobazam Clomipramine Clonazepam Clorazepate Clozapine Codeine Colestipol Corticotropin Cosyntropin Dapagliflozin Deflazacort Desvenlafaxine Dexamethasone Dexlansoprazole Dexmedetomidine Diatrizoate Diazepam Diclofenac Diflunisal Digitoxin Digoxin Dihydrocodeine Dimenhydrinate Diphenhydramine Disopyramide Doxacurium Doxepin Dronabinol Dulaglutide Duloxetine Empagliflozin Enalapril Epoprostenol Ertugliflozin Escitalopram Eslicarbazepine Esmolol Esomeprazole Ethanol Etodolac Exenatide Fenoldopam Fenoprofen Fentanyl Fludrocortisone Fluoxetine Fluphenazine Flurazepam Flurbiprofen Fluvoxamine Formoterol Foscarnet Fosinopril Glimepiride Glipizide Glyburide Glycerin Guanfacine Haloperidol Hydrochlorothiazide Hydrocodone Hydrocortisone Hydroflumethiazide Hydromorphone Hydroxyzine Ibandronate Ibuprofen Iloperidone Iloprost Imipramine Indacaterol Indapamide Indomethacin Insulin Degludec Insulin Detemir Insulin Glargine Insulin Lispro Iodipamide Iodixanol Iohexol Iopamidol Iopromide Iothalamic Acid Ioversol Ioxilan Irinotecan Isocarboxazid Isoetharine Ketoprofen Ketorolac Labetalol Lactitol Lactulose Lansoprazole Levobetaxolol Levobunolol Levodopa Levomilnacipran Licorice Linagliptin Linezolid Liraglutide Lisinopril Lixisenatide Lofexidine Loracarbef Lorazepam Loxapine Lumateperone Lurasidone Magnesium Citrate Magnesium Hydroxide Maprotiline Maraviroc Meclofenamic Acid Mefenamate Meloxicam Meprobamate Mesoridazine Metaproterenol Metformin Methadone Methdilazine Methocarbamol Methotrimeprazine Methoxsalen Methylprednisolone Metipranolol Metocurine Metolazone Metoprolol Midazolam Miglitol Milnacipran Mineral Oil

Showing 240 of 542. Type above to find a specific drug.

Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.

Sources & citations

[1]FDA DailyMed · 056be255-5880-48… · revised January 8, 2025 [PDF]
[2]MHRA (UK) · PL045690434 · revised April 10, 2026
[3]Health Canada (DPD) · 00728276 · revised April 23, 2026
[4]OpenFDA adverse-event reports (US), 12 months ending June 4, 2026.

Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.