Brinzolamide
Carbonic Anhydrase Inhibitors
Sold as Azopt · Azarga · Simbrinza
- Drug class
- Carbonic Anhydrase Inhibitors
- Availability
- Prescription only
- Routes
- Ophthalmic
- Markets covered
- 4
- Products on record
- 53
- FDA reports (12 mo)
- 384
Overview
Plain-language summary, compiled from the cited regulatory records
Brinzolamide is a medication belonging to the drug class of carbonic anhydrase inhibitors [1]. It is approved for the treatment of elevated intraocular pressure (IOP) in individuals diagnosed with ocular hypertension or open-angle glaucoma [1].
This active ingredient is available under various brand names, including Azopt [1]. In the past 12 months, there have been 384 adverse event reports associated with medications containing brinzolamide [2]. The most frequently reported adverse events include eye pain, off-label use, fatigue, diarrhea, and headache [2].
This is not medical advice. Consult a qualified healthcare professional.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| GB United Kingdom | MHRA | 46 | May 1, 2026 |
| EU European Union | EMA | 3 | February 9, 2026 |
| CA Canada | Health Canada | 3 | March 22, 2025 |
| US United States | FDA | 1 | November 24, 2023 |
GBUnited Kingdom· MHRA
46 products
Uses
1).
How to take
EUEuropean Union· EMA
3 products
Uses
1).
How to take
CACanada· Health Canada
3 products
Uses
AZOPT® (brinzolamide ophthalmic suspension) is indicated for: • the treatment of elevated intraocular pressure (IOP) in adult patients with ocular hypertension or open-angle glaucoma. 1 Pediatrics Pediatrics (< 18 years of age): The safety and effectiveness of AZOPT in pediatric patients have not been established; therefore, Health Canada has not authorized an indication for pediatric use.
2 Geriatrics Geriatrics (> 65 years of age): No overall differences in safety and effectiveness have been observed between elderly and other adult patients.
How to take
USUnited States· FDA
1 product
Uses
1 INDICATIONS AND USAGE AZOPT is a carbonic anhydrase inhibitor indicated in the treatment of elevated intraocular pressure (IOP) in patients with ocular hypertension or open-angle glaucoma. AZOPT is a carbonic anhydrase inhibitor indicated for the treatment of elevated intraocular pressure (IOP) in patients with ocular hypertension or open-angle glaucoma.
( 1 )
How to take
Drug interactions
Known interactions involving Brinzolamide. Select one for details. This list is informational and not a complete interaction checker.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]MHRA (UK) · PL044161787 · revised April 21, 2026
- [2]European Medicines Agency · EMEA/H/C/000267 · revised February 9, 2026
- [3]Health Canada (DPD) · 02238873 · revised March 22, 2025
- [4]FDA DailyMed · 0afb6589-51ba-43… · revised November 24, 2023 [PDF]
- [5]OpenFDA adverse-event reports (US), 12 months ending June 4, 2026.
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.