Amiodarone
Antiarrhythmics, Class Iii
- Drug class
- Antiarrhythmics, Class Iii
- Availability
- Prescription only
- Routes
- Oral, Intravenous
- Markets covered
- 3
- Products on record
- 35
Overview
Plain-language summary, compiled from the cited regulatory records
Amiodarone is an antiarrhythmic medication belonging to Class III [1]. It is approved for initiating treatment and preventing recurrent ventricular fibrillation (VF) and hemodynamically unstable ventricular tachycardia (VT) in patients who have not responded to other therapies [1]. Amiodarone injection may also be used for patients with VT/VF who require treatment but cannot take oral medication [1]. Patients may transition to oral amiodarone during or after treatment with the injectable form [1].
This medication is available under various brand names [1].
This is not medical advice. Consult a qualified healthcare professional.
Regulatory status by market
| Market | Regulator | Products | Last revision |
|---|---|---|---|
| GB United Kingdom | MHRA | 27 | May 29, 2026 |
| CA Canada | Health Canada | 5 | June 1, 2026 |
| US United States | FDA | 3 | April 20, 2026 |
GBUnited Kingdom· MHRA
27 products
Uses
Treatment should be initiated and normally monitored only under hospital or specialist supervision. Oral Amiodarone Hydrochloride 200mg Tablets are indicated only for the treatment of severe rhythm disorders not responding to other therapies or when other treatments cannot be used.
Tachyarrhythmias associated with Wolff-Parkinson-White Syndrome. Atrial flutter and fibrillation when other drugs cannot be used. All types of tachyarrhythmias of paroxysmal nature including: supraventricular, nodal and ventricular tachycardias, ventricular fibrillation; when other drugs cannot be used.
Tablets are used for stabilisation and long term treatment.
How to take
CACanada· Health Canada
5 products
Uses
AND CLINICAL USE ................................................................................................... 3 CONTRAINDICATIONS ........................................................................................................................
4 WARNINGS AND PRECAUTIONS ....................................................................................................... 4 ADVERSE REACTIONS .......................................................................................................................
15 DRUG INTERACTIONS ....................................................................................................................... 18 DOSAGE AND ADMINISTRATION ...................................................................................................
22 OVERDOSAGE ..................................................................................................................................... 26 ACTION AND CLINICAL PHARMACOLOGY..................................................................................
USUnited States· FDA
3 products
Uses
1 INDICATIONS AND USAGE Amiodarone hydrochloride tablets are indicated for the treatment of documented, life-threatening recurrent ventricular fibrillation and life-threatening recurrent hemodynamically unstable tachycardia in adults who have not responded to adequate doses of other available antiarrhythmics or when alternative agents cannot be tolerated.
Amiodarone hydrochloride is an antiarrhythmic indicated for: • Recurrent ventricular fibrillation. (1) • Recurrent hemodynamically unstable ventricular tachycardia. (1)
How to take
Drug interactions
Known interactions involving Amiodarone. Select one for details. This list is informational and not a complete interaction checker.
Showing 240 of 600. Type above to find a specific drug.
Interaction data compiled from DDInter (academic, CC-BY). Severity classification only - this is not a complete interaction checker and not medical advice.
Sources & citations
- [1]MHRA (UK) · PL556120082 · revised May 29, 2026
- [2]Health Canada (DPD) · 02249502 · revised March 22, 2025
- [3]FDA DailyMed · 0caedb97-56fd-4e… · revised April 20, 2026 [PDF]
Information on this page is compiled from public regulatory records. Drugvu is not affiliated with any regulator or pharmaceutical manufacturer. This is not medical advice. Always consult a qualified healthcare professional.