PARASERTS is a brand name for Acetaminophen (also known as Paracetamol). The medicine, its uses, side effects and dosage are the same regardless of brand.
Used for: For the treatment of mild to moderate pain and fever. Paraserts/Paracetamol Suppositories may be especially useful in patients unable to take oral forms of paracetamol, e.g. post-operatively or with nausea and vomiting.
Verbatim from this product's MHRA label. Tap a section to expand.
Method of administration:
Rectal Children 10 years – 12 years (30-40kg): 1 suppository every 4 to 6 hours up to a maximum of 4 suppositories in 24 hours. Adults + Children 12 years and over: 1 -2 suppositories every 4 to 6 hours up to a maximum of 8 suppositories in 24 hours.
Dosages should be based on the child’s age and weight. The dose should not be repeated more frequently than every 4 hours. The recommended dose should not be exceeded. Higher doses do not produce any increase in analgesic effect. The product should not be used for more than 3 days, except on the advice of a doctor.
Only whole suppositories should be administered – do not break the suppository before administration
Common Miscellaneous:
Redness of the rectal mucous membranes >1/100 Rare General: Allergic reactions including skin rashes <1/1000 Skin: Exanthema, urticaria Liver: Liver damage Genitourinary: Increase in creatinine (mostly secondary to hepatorenal syndrome) Not Known (cannot be estimated from the available data) Metabolism and nutrition disorders: High anion gap metabolic acidosis There have been some reports of blood dyscrasias including thrombocytopenia and argranulocytosis, with the use of paracetamol- containing products, but the causal relationship has not been established.
4). Pyroglutamic acidosis may occur as a consequence of low glutathione levels in these patients. Reporting of suspected adverse reactions Reporting suspected adverse reactions after authorisation of the medicinal product is important.
It allows continued monitoring of the benefit/risk balance of the medicinal product. uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.
Paraserts/Paracetamol Suppositories should not be combined with other analgesic medications that contain paracetamol. Paracetamol should be given with care to patients with impaired kidney or liver function. In general, the habitual use of painkillers, especially with combinations of more than one pain killing active ingredient, can lead to permanent kidney damage with the risk of liver failure (analgesic nephropathy).
Label and leaflet will state the following warnings:
Label: “Immediate medical advice should be sought in the event of an overdose, even if the child seems well”. g. chronic alcoholism) who were treated with paracetamol at therapeutic dose for a prolonged period or a combination of paracetamol and flucloxacillin.
If HAGMA due to pyroglutamic acidosis is suspected, prompt discontinuation of paracetamol and close monitoring is recommended. The measurement of urinary 5-oxoproline may be useful to identify pyroglutamic acidosis as underlying cause of HAGMA in patients with multiple risk factors.
1, soy or peanuts.
Not medical advice. Always read the patient information leaflet and follow your prescriber or pharmacist.
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