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OXYCONTIN is a brand name for Oxycodone. The medicine, its uses, side effects and dosage are the same regardless of brand.
Used for: For the treatment of moderate to severe pain in patients with cancer. For the treatment of severe pain requiring the use of a strong opioid. 4.2Posology and method of administration Adults over 18 years: OxyContin tablets should be taken at 12-hourly intervals. The dosage is dependent on the severity of the pain, and…
Verbatim from this product's MHRA label. Tap a section to expand.
5). The primary risk of opioid excess is respiratory depression. Sleep related breathing disorders Opioids can cause sleep-related breathing disorders including central sleep apnoea (CSA) and sleep-related hypoxemia. Opioid use increases the risk of CSA in a dose-dependent fashion.
In patients who present with CSA, consider decreasing the total opioid dosage. 8). Concomitant use of oxycodone and sedative medicines such as benzodiazepines or related drugs may result in sedation, respiratory depression, coma and death.
Because of these risks, concomitant prescribing with these sedative medicines should be reserved for patients for whom alternative treatment options are not possible. 2). The patient should be followed closely for signs and symptoms of respiratory depression and sedation.
5). OxyContin tablets must be administered with caution in patients taking MAOIs or who have received MAOIs within the previous two weeks. OxyContin tablets should not be used where there is a possibility of paralytic ileus occurring.
Should paralytic ileus be suspected or occur during use, OxyContin tablets should be discontinued immediately. OxyContin tablets are not recommended for pre-operative use or within the first 12-24 hours post-operatively. Prolonged release opioids should not be used for acute post-operative pain owing to the increased risk of persistent post-operative opioid use (PPOU) and opioid-induced ventilatory impairment (OIVI).
As with all opioid preparations, oxycodone products should be used with caution following abdominal surgery as opioids are known to impair intestinal motility and should not be used until the physician is assured of normal bowel function.
g. surgery, plexus blockade) should not receive OxyContin tablets for 12 hours prior to the intervention. If further treatment with OxyContin tablets is indicated then the dosage should be adjusted to the new post-operative requirement.
For appropriate patients who suffer with chronic non-malignant pain, opioids should be used as part of a comprehensive treatment programme involving other medications and treatment modalities. A crucial part of the assessment of a patient with chronic non-malignant pain is the patient’s addiction and substance abuse history.
If opioid treatment is considered appropriate for the patient, then the main aim of treatment is not to minimise the dose of opioid but rather to achieve a dose, which provides adequate pain relief with a minimum of side effects. 2 for additional information on treatment goals and discontinuation.
Not medical advice. Always read the patient information leaflet and follow your prescriber or pharmacist.
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Tolerance, Dependence and Opioid Use Disorder Tolerance and physical and/or psychological dependence may develop upon repeated administration of opioids such as oxycodone. Repeated use of OxyContin tablets may lead to Opioid Use Disorder (OUD).
A higher dose and longer duration of opioid treatment can increase the risk of developing OUD. Abuse or intentional misuse of OxyContin tablets may result in overdose and/or death. g. major depression, anxiety and personality disorders).
2). Before and during treatment the patient should also be informed about the risks and signs of OUD. If these signs occur, patients should be advised to contact their physician. g. too early requests for refills). The prescriber should conduct a review of concomitant opioids and psycho-active drugs (like benzodiazepines).
For patients with signs and symptoms of OUD, consultation with an addiction specialist should be considered. A comprehensive patient history should be taken to document concomitant medications, including over-the-counter medicines and medicines obtained on-line, and past and present medical and psychiatric conditions.
Patients may find that treatment is less effective with chronic use and express a need to increase the dose to obtain the same level of pain control as initially experienced. Patients may also supplement their treatment with additional pain relievers.
These could be signs that the patient is developing tolerance. The risks of developing tolerance should be explained to the patient. Overuse or misuse may result in overdose and/or death. It is important that patients only use medicines that are prescribed for them at the dose they […]