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Brand of Ibuprofen
NUROFEN FOR CHILDREN COLD PAIN AND FEVER STRAWBERRY FLAVOUR is a brand name for Ibuprofen. The medicine, its uses, side effects and dosage are the same regardless of brand.
Used for: Prescription and OTC: For the fast and effective reduction of fever, including post immunisation pyrexia and the fast and effective relief of the symptoms of colds and influenza and mild to moderate pain, such as a sore throat, teething pain, toothache, headache, minor aches and sprains.
Verbatim from this product's MHRA label. Tap a section to expand.
4). For short term use only. The recommended daily dose of the product is 20 – 30 mg per kg of body weight, divided into equal doses, with dosing intervals of 6 to 8 hours. Leave at least 4 hours between doses and do not take more than the recommended dose in 24 hours.
The recommended dose should not be exceeded. 5ml spoonful) may be taken 3 times in 24 hours Children 7-9 years 21-30 two 5ml doses may be taken 3 times in 24 hours Not suitable for children under 3 months of age. Do not use this product in children weighing less than 5 kg.
For infants aged 3-6 months medical advice should be sought if symptoms worsen or not later than 24 hours if symptoms persist. If in children aged from 6 months this medicinal product is required for more than 3 days, or if symptoms worsen a doctor should be consulted.
Special patient groups: • For children with Juvenile Rheumatoid Arthritis:
The usual daily dose of up to 30 to 40 mg per kg of body weight, in three to four divided doses may be taken. 5 ml dose 6 hours later if necessary. 5ml doses in 24 hours. If the fever is not reduced, consult a doctor. Method of administration For oral administration.
For patients with sensitive stomachs the product can be taken with or after food.
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8) Renal tubular acidosis and hypokalaemia may occur following acute overdose and in patients taking ibuprofen products over long periods at high doses (typically greater than 4 weeks), including doses exceeding the recommended daily dose.
8) Impaired female fertility: There is limited evidence that drugs which inhibit cyclo-oxygenase/ prostaglandin synthesis may cause impairment of female fertility by an effect on ovulation. This is reversible upon withdrawal of treatment.
8). Gastrointestinal bleeding, ulceration or perforation, which can be fatal, has been reported with all NSAIDs at anytime during treatment, with or without warning symptoms or a previous history of serious GI events. 3), and in the elderly.
These patients should commence treatment on the lowest dose available. Patients with a history of GI toxicity, particularly when elderly, should report any unusual abdominal symptoms (especially GI bleeding) particularly in the initial stages of treatment.
5). When GI bleeding or ulceration occurs in patients receiving ibuprofen, the treatment should be withdrawn. 8). Most of these reactions occurred within the first month. If signs and suggestive of these reactions appear, ibuprofen should be withdrawn immediately, and an alternative treatment considered (as appropriate).
Masking of symptoms of underlying infections This medicine can mask symptoms of infection, which may lead to delayed initiation of appropriate treatment and thereby worsening the outcome of the infection. This has been observed in bacterial community acquired pneumonia and bacterial complications to varicella.
When this medicine is administered for fever or pain relief in relation to infection, monitoring of infection is advised. In non-hospital settings, the patient should consult a doctor if symptoms persist or worsen. Exceptionally, varicella can be at the origin of serious cutaneous and soft tissues infectious complications.
Thus, it is advisable to avoid use of Nurofen for Children in case of varicella. This product contains Maltitol and Propylene glycol. Patients with rare hereditary problems of fructose intolerance should not take this medicine.
The label will include:
Read the leaflet before use. Warning: do not take more medicine than the label tells you to. 4). Experimental data suggest that ibuprofen may inhibit the effect of low dose acetylsalicylic acid (aspirin) on platelet aggregation when they are dosed concomitantly.
1). 4).
Antihypertensives (ACE inhibitors and Angiotensin II Antagonists) and diuretics:
NSAIDs may diminish the effect of these drugs. Diuretics can increase the risk of nephrotoxicity of NSAIDs. 4). Cardiac […]
Undesirable effects may be minimised by using the lowest effective dose for the shortest duration necessary to control symptoms (see GI and cardiovascular risks below). The elderly have an increased frequency of adverse reactions to NSAIDs especially gastrointestinal bleeding and perforation which may be fatal.
Respiratory:
Bronchospasm may be precipitated in patients suffering from or with a previous history of bronchial asthma or allergic disease. 5). 8) Cardiovascular and cerebrovascular effects: Cases of Kounis syndrome have been reported in patients treated with Nurofen Express 256 mg Tablets.
Kounis syndrome has been defined as cardiovascular symptoms secondary to an allergic or hypersensitive reaction associated with constriction of coronary arteries and potentially leading to myocardial infarction. Caution (discussion with doctor or pharmacist) is required prior to starting treatment in patients with a history of hypertension and/or heart failure as fluid retention, hypertension and oedema have been reported in association with NSAID therapy.
Clinical trial and epidemiological data suggest that use of ibuprofen, particularly at high doses (2400mg daily) and in long-term treatment may be associated with a small increased risk of arterial thrombotic events (for example myocardial infarction or stroke).
g. ≤ 1200mg daily) is associated with an increased risk of myocardial infarction. 8) Renal tubular acidosis and hypokalaemia may occur following acute overdose and in patients taking ibuprofen products over long periods at high doses (typically greater than 4 weeks), including doses exceeding the recommended daily dose.
8) Impaired female fertility: There is limited evidence that drugs which inhibit cyclo-oxygenase/ prostaglandin synthesis may cause impairment of female fertility by an effect on ovulation. This is reversible upon withdrawal of treatment.
8). Gastrointestinal bleeding, ulceration or perforation, which can be fatal, has been reported with all NSAIDs at anytime during treatment, with or without warning symptoms or a previous history of serious GI events. 3), and in the elderly.
These patients should commence treatment on the lowest dose available. Patients with a history of GI toxicity, particularly when elderly, should report any unusual abdominal symptoms (especially GI bleeding) particularly in the initial stages of treatment.
5). When GI bleeding or ulceration occurs in patients receiving ibuprofen, the treatment should be withdrawn. 8). Most of these reactions occurred within the first month. If signs and suggestive of these reactions appear, ibuprofen should be withdrawn immediately, and an alternative treatment considered (as appropriate).
Masking of symptoms of underlying infections This medicine can mask symptoms of infection, which may lead to delayed initiation of appropriate treatment and thereby worsening the outcome of the infection. This has been observed in bacterial community acquired pneumonia and bacterial complications to varicella.
When this medicine is administered for fever or pain relief in relation to infection, monitoring of infection is advised. In non-hospital settings, the patient should consult a doctor if symptoms persist or worsen. Exceptionally, varicella can be at the origin of serious cutaneous and soft tissues infectious complications.
Thus, it is advisable to avoid use of Nurofen for Children in case of varicella. This product contains Maltitol and Propylene glycol. Patients with rare hereditary problems of fructose intolerance should not take this medicine.
The label will include:
Read the leaflet before use. Warning: do not take more medicine than the label tells you to. Do not give this product if the child: • is under 3 months old or weighs less than 5 kg • has (or has had two or more episodes of) a stomach ulcer, perforation or bleeding • is allergic to ibuprofen or any other ingredient of the product, aspirin or other related painkillers, or fructose • is taking other NSAID painkillers, or aspirin with a daily dose above 75 mg Consult a doctor or pharmacist before use for: • someone who has or had asthma, diabetes, high cholesterol, high […]
1. g. asthma, rhinitis, angioedema or urticaria) in response to ibuprofen, acetylsalicylic acid (aspirin) or other non-steroidal anti-inflammatory drugs (NSAIDs). Active or a history of recurrent peptic ulcer/haemorrhage (two or more distinct episodes of proven ulceration or bleeding).
History of gastrointestinal bleeding or perforation, related to previous NSAIDs therapy. 4, Special warnings and precautions for use). 6 Pregnancy and lactation).
Not medical advice. Always read the patient information leaflet and follow your prescriber or pharmacist.