INSTILLAGEL

Unless otherwise prescribed by a doctor: a) Urethral sounding and catheterisation: instill 6-11 ml. After the usual cleaning of the glans and urethra and orifice, Instillagel® is instilled into the urethra and the glans is pressed for a short time between the thumb and index finger until the anaesthetic effect begins.

When narrow gauge catheters are being introduced, any blockage of the eye of the catheter by gel can either be eliminated, if the bladder is full, by light pressure on the hypogastrium producing discharge of urine, or re-opened by means of the sterile disposable syringe and instillation of sterile saline solution.

b) Cystoscopy: with a view to considerate and painless introduction of instruments, the entire urethra including the external sphincter must be coated with a film of lubricant and anaesthetised. With a short penis and correspondingly narrow urethra, a dose of 11 ml is sufficient; in other cases an additional instillation of 6-11 ml of Instillagel® is recommended.

A penis clamp is applied in the area of the coronary sulcus. 5 minutes. In prograde ureterocystoscopy the external sphincter, which is simultaneously anaesthetised, can distinctly be seen opening up when irrigated.

In spite of the proven wide safety range of Instillagel, undesirable effects of the local anaesthetic, lidocaine, are possible where there is severe injury to the mucosa and absorption may occur. Examples are anaphylaxis, fall in blood pressure, bradycardia or convulsions.

4). Reporting of suspected adverse reactions Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. uk/yellowcard.

4 Special warnings and special precautions for use Products containing local anaesthetics should also be used with caution in patients with impaired cardiac conditions, hepatic insufficiency and in epileptics. Oropharyngeal use of Instillagel may cause difficulty in swallowing and therefore an increased risk of aspiration due to its local anaesthetic effect.

Numbness of the tongue and buccal mucosa may also increase the chance of biting trauma. 9 ‘Overdose’. Instillagel contains methyl hydroxybenzoate and propyl hydroxybenzoate, which may cause allergic reactions (possible delayed). 75 g propylene glycol in each syringe of 11 ml.

5 mg/ml. Propylene glycol may cause skin irritation. Instillagel must not come into contact with the eye. Serious cases of persistent corneal injury, potentially requiring corneal transplant, were reported following accidental ocular exposure to chlorhexidine containing medicinal products despite taking eye protective measures due to migration of solution beyond the intended surgical preparation area.

Extreme care must be taken during application to ensure that Instillagel does not migrate beyond its intended application site into the eyes. Particular care should be taken in anaesthetised patients, who are unable to immediately report ocular exposure.

If Instillagel comes into contact with the eyes, wash out promptly and thoroughly with water. An ophthalmologist’s advice should be sought.

Instillagel® must not be used in patients with known hypersensitivity to the active ingredients (amide-type anaesthetics, chlorhexidine and alkyl hydroxybenzoates) or any of the excipients. Instillagel® should not be used in patients who have damaged or bleeding mucous membranes because of the risk of systemic absorption of the lidocaine hydrochloride.