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FRUSOL is a brand name for Furosemide (also known as Frusemide). The medicine, its uses, side effects and dosage are the same regardless of brand.
Used for: Furosemide is indicated in all conditions requiring prompt diuresis, including cardiac, pulmonary, hepatic and renal oedema, peripheral oedema due to mechanical obstruction or venous insufficiency and hypertension. It is also indicated for the maintenance therapy of mild oedema of any origin.
Verbatim from this product's MHRA label. Tap a section to expand.
Posology Adults The usual initial daily dose is 40mg. This may be adjusted until an effective dose is achieved. Paediatric population 1 to 3mg/Kg body weight daily up to a maximum total dose of 40mg/day. Elderly In the elderly, Furosemide is generally eliminated more slowly.
Dosage should be titrated until the required response is achieved. Method of administration For oral use. Suitable for administration via nasogastric (NG) or percutaneous endoscopic gastrostomy (PEG) tubes. 6. The medication should be administered in the morning to avoid nocturnal diuresis.
Very common (≥1/10); common (≥1/100 to <1/10); uncommon (≥1/1,000 to <1/100); rare (≥1/10,000 to <1/1,000); very rare (<1/10,000); Frequency not known (cannot be estimated from the available data). Uncommon: aplastic anaemia Rare: bone marrow depression (necessitates withdrawal of treatment), eosinophilia, leucopenia.
Blood and lymphatic system disorders:
Very rare: haemolytic anaemia, agranulocytosis, thrombocytopenia Very common: dehydration, hyponatraemia, hypochloremic metabolic alkalosis, hypocalcaemia, hypomagnesemia (incidences of the last three are reduced by triamterene) Common: Hypovolaemia, hypochloraemia Uncommon: impaired glucose tolerance (by hypokalaemia) hyperuricaemia, gout, reduction of serum HDL-cholesterol, elevation of serum LDL-cholesterol, elevation of serum triglycerides, hyperglycaemia.
Very rare: tetany Metabolism and nutritional disorders:
Frequency not known: aggravated pre-existing metabolic alkalosis (in decompensated cirrhosis of the liver), fluid and electrolyte disturbances, excretion of potassium increased* In patients with diabetes mellitus this may lead to deterioration of metabolic control; latent diabetes mellitus may become manifest Psychiatric disorder: Rare: psychiatric disorder NOC Rare: paraesthesia, confusion, headacheNervous system disorders: Not known: dizziness, fainting and loss of consciousness (caused by symptomatic hypotension) Eye disorders: Uncommon: visual disturbance, blurred vision, yellow vision.
g. in nephritic syndrome) Cardiac disorders: Uncommon: orthostatic intolerance, cardiac arrhythmias, increased risk or persistence of patent ductus arteriosus in premature infants. Very common: hypotension, (which, if pronounced may cause signs and symptoms such as impairment of concentration and reactions, light-headedness, sensations of pressure in the head, headache, drowsiness, weakness, disorders of vision, dry mouth, orthostatic intolerance).
4 Digitalis intoxication Section
1 or sulphonamides, sulphonamide derivatives. Hypovolaemia and dehydration (with or without accompanying hypotension) Section
Not medical advice. Always read the patient information leaflet and follow your prescriber or pharmacist.
Other brands of Furosemide in United Kingdom.
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Brand names are compiled from public regulatory records for active-ingredient mapping only. Drugvu is not affiliated with any manufacturer. This is not medical advice.
Vascular disorders:
Rare: vasculitis, thrombosis, shock Uncommon: dry mouth, thirst, nausea, bowel motility disturbances, vomiting, diarrhoea, constipation Gastrointestinal disorders: Rare: acute pancreatitis (in long-term diuretic treatment, including furosemide).
Rare: pure intrahepatic cholestasis (jaundice), hepatic function abnormal.
Hepatobiliary disorders:
Frequency not known: Hepatic encephalopathy in patients with hepatocellular insufficiency may occur. Rare: rash, pruritus, photosensitivity, toxic epidermal necrolysis.
Skin and subcutaneous tissue disorders:
Frequency not known: urticaria, erythema multiforme, purpura, exfoliative dermatitis, itching, allergic reactions, such as skin rashes, various forms of dermatitis including urticaria, bullous lesions, acute generalised exanthematous pustulosis (AGEP).
When these occur treatment should be withdrawn.
Steven-Johnson’s syndrome Musculoskeletal and connective tissue disorders:
Uncommon: muscle cramps, muscle weakness.
Very common: nephrocalcinosis in infantsRenal and urinary disorders:
Uncommon: reduced diuresis, urinary incontinence, urinary obstruction (in patients with hyperplasia of the prostate, bladder inability to empty, urethral stricture unspecified). Rare: interstitial nephritis, acute renal failure. g. with shock).
Investigations:
Common: creatinine increased, blood urea increased Rare: Transaminases increased, blood *Potassium deficiency manifests itself in neuromuscular symptoms (muscular weakness, paralysis), intestinal symptoms (vomiting, constipation meterorism), renal symptoms (polyuria) or cardiac symptoms.
Severe potassium depletion can result in paralytic ileus or confusion, which can result in coma. Reporting of suspected adverse reactions Reporting suspected adverse reactions after authorisation of the medicinal product is important.
It allows continued monitoring of the benefit/risk balance of the medicinal product. uk/yellowcard.