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CO-DANTHRUSATE is a brand name for Docusate. The medicine, its uses, side effects and dosage are the same regardless of brand.
Used for: Constipation in terminally ill patients of all ages
Verbatim from this product's MHRA label. Tap a section to expand.
Posology Adults and elderly Co-danthrusate Capsules are given in doses of 1-3 capsules in adults including elderly patients. Paediatric population Children between the ages of 6 to 12 years are given 1 capsule. Doses are usually given at bedtime.
Children under 6 years - not recommended.
Method of Administration:
Oral
Occasionally an orange tint in the urine may be observed due to the dantron component. A mild griping feeling in the abdomen may occur. Skin rash may occur and reports of skin irritation, skin discolouration and superficial sloughing of the perianal skin have been reported after prolonged use of co- danthrusate.
Prolonged use or high doses of stimulant laxatives like co-danthrusate may lead to fluid and electrolyte imbalance, colonic atony, melanosis coli (discolouration of the colonic mucosa) and tolerance to their effects. Reporting of suspected adverse reactions Reporting suspected adverse reactions after authorisation of the medicinal product is important.
It allows continued monitoring of the benefit/risk balance of the medicinal product. uk/yellowcard.
In experimental animals, Dantron has been associated with adenocarcinomas in the bowel and tumours in the liver. A theoretical risk of similar effects in humans cannot be excluded. Dantron is excreted in the urine and metabolised dantron in the faeces.
There is evidence that these may cause perineal erythema in patients with urinary and or faecal incontinence. It is recommended therefore that co-danthrusate should be used with caution in all incontinent patients. Prolonged use is not recommended.
Dantron-containing laxatives like co-danthrusate should not be used for the general management of constipation in the elderly. Co-danthrusate capsules contain lactose. Patients with rare hereditary problems of galactose intolerance, fructose intolerance, sucrose-isomaltase insufficiency, the lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine.
1. Like all laxatives, Co-danthrusate is contraindicated in cases of intestinal obstruction or undiagnosed abdominal pain.
Not medical advice. Always read the patient information leaflet and follow your prescriber or pharmacist.
Other brands of Docusate in United Kingdom.
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Brand names are compiled from public regulatory records for active-ingredient mapping only. Drugvu is not affiliated with any manufacturer. This is not medical advice.