Loading…
CO-CODAMOL is a brand name for Acetaminophen (also known as Paracetamol). The medicine, its uses, side effects and dosage are the same regardless of brand.
Used for: Codeine is indicated in patients older than 12 years of age for the treatment of acute moderate pain which is not considered to be relieved by other analgesics such as paracetamol or ibuprofen (alone). For the symptomatic relief of pain including headache, migraine, toothache, period pains, rheumatic pains, including…
Verbatim from this product's MHRA label. Tap a section to expand.
For oral use.
Adults:
One or two tablets to be swallowed with water. The dose should not be repeated more frequently than every four to six hours and not more than four times in any 24 hour period. 0g of paracetamol and 64mg of codeine in divided doses) per 24 hours.
Elderly:
The dosage should be reduced.
Hepatic impairment:
The dosage should be reduced. Use in liver disease is contraindicated (see
). 4 Special Warnings and Precautions for Use.
Paediatric population:
Children aged 16 to 18 years: One to two tablets every six hours when necessary to a maximum of eight tablets per 24 hours. 0g of paracetamol and 32mg of codeine in divided doses) per 24 hours. The duration of treatment should be limited to 3 days and if no effective pain relief is achieved the patients/carers should be advised to seek the views of a physician.
4). 3 Contraindications i. Paracetamol: • Hypersensitivity to paracetamol or any of the excipients. ii. Codeine: • Acute respiratory depression • Hypersensitivity to codeine or other opioid analgesics, or to any of the excipients. • Liver disease.
• Acute alcoholism. • Use should be avoided in patients with raised intracranial pressure or head injury (in addition to the risk of respiratory depression and increased intracranial pressure, may affect pupillary and other responses vital for neurological assessment).
6) • In patients for whom it is known they are CYP2D6 ultra-rapid metabolisers • Concomitant use of monoamine oxidase inhibitors (MAOIs) or within two weeks of MAOI discontinuation as severe CNS excitation or depression (including hypertension or hypotension) may occur.
g. pseudomembranous colitis). Not to be used in children of 12 years and under. 4 Special warnings and precautions for use i.
Paracetamol:
Care is advised in the administration of paracetamol to patients with renal or hepatic impairment. The hazards of overdose are greater in those with non- cirrhotic alcoholic liver disease. Paracetamol should be given with care to patients with alcoholic dependence.
Paracetamol is well tolerated by the majority of people with asthma. However, a small percentage of aspirin sensitive asthmatics are also sensitive to paracetamol. 8 Undesirable Effects). 5 Interactions). Do not exceed the recommended dose.
Paediatric population:
Children aged 16 to 18 years: One to two tablets every six hours when necessary to a maximum of eight tablets per 24 hours. 0g of paracetamol and 32mg of codeine in divided doses) per 24 hours. The duration of treatment should be limited to 3 days and if no effective pain relief is achieved the patients/carers should be advised to seek the views of a physician.
4). 3 Contraindications i. Paracetamol: • Hypersensitivity to paracetamol or any of the excipients. ii. Codeine: • Acute respiratory depression • Hypersensitivity to codeine or other opioid analgesics, or to any of the excipients. • Liver disease.
• Acute alcoholism. • Use should be avoided in patients with raised intracranial pressure or head injury (in addition to the risk of respiratory depression and increased intracranial pressure, may affect pupillary and other responses vital for neurological assessment).
6) • In patients for whom it is known they are CYP2D6 ultra-rapid metabolisers • Concomitant use of monoamine oxidase inhibitors (MAOIs) or within two weeks of MAOI discontinuation as severe CNS excitation or depression (including hypertension or hypotension) may occur.
g. pseudomembranous colitis). Not to be used in children of 12 years and under. 4 Special warnings and precautions for use i.
Paracetamol:
Care is advised in the administration of paracetamol to patients with renal or hepatic impairment. The hazards of overdose are greater in those with non- cirrhotic alcoholic liver disease. Paracetamol should be given with care to patients with alcoholic dependence.
Paracetamol is well tolerated by the majority of people with asthma. However, a small percentage of aspirin sensitive asthmatics are also sensitive to paracetamol. 8 Undesirable Effects). Caution should be exercised when using paracetamol prior to (less than 72 hours) or concurrently with intravenous busulfan (see section
). 8 Undesirable Effects). For concomitant illnesses/conditions where dose reduction may be appropriate, see
Not medical advice. Always read the patient information leaflet and follow your prescriber or pharmacist.
Other brands of Acetaminophen in United Kingdom.
Know a brand we are missing in United Kingdom? Suggest a brand →
Brand names are compiled from public regulatory records for active-ingredient mapping only. Drugvu is not affiliated with any manufacturer. This is not medical advice.
Patients should be advised not to take other paracetamol- containing products concurrently. g. chronic alcoholism) who were treated with paracetamol at therapeutic dose for a prolonged period or a combination of paracetamol and flucloxacillin.
If HAGMA due to pyroglutamic acidosis is suspected, prompt discontinuation of paracetamol and close monitoring, is recommended. The measurement of urinary 5-oxoproline may be useful to identify pyroglutamic acidosis as underlying cause of HAGMA in patients with multiple risk factors.
Label:
Do not take more medicine than the label tells you to. If you do not get better, talk to your doctor. Contains paracetamol. Do not take anything else containing paracetamol while taking this medicine. Talk to a doctor at once if you take too much of this medicine, even if you feel well.
Leaflet:
Talk to a doctor at once if you take too much of this medicine even if you feel well. This is because too much paracetamol can cause delayed, serious liver damage. ii.
Codeine:
Use in reduced doses or with caution in asthma, and decreased respiratory reserve. 3 Contraindications). It should only be used with caution or in reduced dose in elderly or debilitated patients, hypotension, hypothyroidism, inflammatory or obstructive bowel disorders, urethral stricture, adrenocortical insufficiency, prostatic hypertrophy, shock, convulsive disorders, myasthenia gravis.
2 posology). Opioid analgesics should be avoided in patients with biliary tract disorders or used in conjunction with an antispasmodic. Administration of pethidine and possibly other opioid analgesics to patients taking a monoamine oxidase inhibitor (MAOI) has been associated with very severe and sometimes fatal reactions.
5). Alcohol should be avoided whilst under treatment with codeine. It should be used with caution in those with a history of drug abuse. Discontinuation should be carried out gradually in patients who may have developed physical dependence, to avoid precipitating withdrawal symptoms.
Risks from concomitant use of opioids and benzodiazepines Concomitant use of opioids, including codeine, with benzodiazepines may result in sedation, respiratory depression, coma and death. Because of these risks, reserve concomitant prescribing of opioids and benzodiazepines for use in patients for […]