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CHLORHEXIDINE ACETATE is a brand name for Chlorhexidine. The medicine, its uses, side effects and dosage are the same regardless of brand.
Used for: Chlorhexidine Acetate BP is a disinfectant which is effective against a wide range of vegetative gram-positive and gram-negative bacteria.
Verbatim from this product's MHRA label. Tap a section to expand.
Dosage Dosage and duration of administration are to be individualized and depend upon the indication for use, the patient’s age, weight, clinical condition, and concomitant treatment, and on patient’s clinical response to treatment (See Section
8 Adverse Reactions). If any signs or symptoms of a suspected hypersensitivity reaction develop, immediately stop use. Appropriate therapeutic countermeasures must be instituted as clinically indicated. Chemical Burns in Neonates The use of chlorhexidine solutions, both alcohol based and aqueous, for skin antisepsis prior to invasive procedures has been associated with skin reactions such as chemical burns in neonates.
This risk appears to be higher in preterm infants, especially those born before 32 weeks of gestation and within the first 2 weeks of life. Remove any soaked materials, drapes or gowns before proceeding with the intervention. Do not use excessive quantities and do not allow the solution to pool in skin folds or under the patient or drip on sheets or other material in direct contact with the patient.
Where occlusive dressings are to be applied to areas previously exposed to chlorhexidine, care must be taken to ensure no excess product is present prior to application of the dressing. 3 Contraindications). Chlorhexidine must not come into contact with the eye.
Serious cases of persistent corneal injury, potentially requiring corneal transplant, were reported following accidental ocular exposure to chlorhexidine containing medicinal products despite taking eye protective measures due to migration of solution beyond the intended surgical preparation area.
Extreme care must be taken during application to ensure that chlorhexidine does not migrate beyond its intended application site into the eyes. Particular care should be taken in anesthetized patients, who are unable to immediately report ocular exposure.
If chlorhexidine comes into contact with the eyes, wash out promptly and thoroughly with water. An ophthalmologist’s advice should be sought. 4 Warnings – Chemical Burns in Neonates). 5 Interaction with other medicinal products and other forms of interaction The activity of chlorhexidine is reduced or neutralized by an alkaline pH, the presence of organic matter, anionic detergents, and tannins.
4 Chemical Burns in Neonates and Preoperative Skin Preparation). 02% w/v for Irrigation is recommended for general topical use when antibacterial irrigation is indicated, including wound and burn irrigation and for the disinfection of respirators.
Not for intravenous or oral route of administration. 4 Special Warnings and Precautions for Use). 4 Special warnings and precautions for use This product should only be used in specialist units familiar with the appropriate selection of patients.
This solution is not to be taken orally. This solution is not for intravenous administration. Accidental ingestion should be treated with a stomach lavage consisting of milk, egg white, gelatine or mild soap. Idiosyncratic reactions to Chlorhexidine Acetate BP have been reported.
Not for use in body cavities Hypersensitivity Reactions Hypersensitivity reactions, including anaphylactic/anaphylactoid reactions, have been reported with chlorhexidine. 8 Adverse Reactions). If any signs or symptoms of a suspected hypersensitivity reaction develop, immediately stop use.
Appropriate therapeutic countermeasures must be instituted as clinically indicated. Chemical Burns in Neonates The use of chlorhexidine solutions, both alcohol based and aqueous, for skin antisepsis prior to invasive procedures has been associated with skin reactions such as chemical burns in neonates.
This risk appears to be higher in preterm infants, especially those born before 32 weeks of gestation and within the first 2 weeks of life. Remove any soaked materials, drapes or gowns before proceeding with the intervention. Do not use excessive quantities and do not allow the solution to pool in skin folds or under the patient or drip on sheets or other material in direct contact with the patient.
Where occlusive dressings are to be applied to areas previously exposed to chlorhexidine, care must be taken to ensure no excess product is present prior to application of the dressing. 3 Contraindications). Chlorhexidine must not come into contact with the eye.
" Do not use in the eye, auditory canal (especially in perforated eardrums), or near meninges, brain or spinal cord (See Section
Not medical advice. Always read the patient information leaflet and follow your prescriber or pharmacist.
Other brands of Chlorhexidine in United Kingdom.
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Brand names are compiled from public regulatory records for active-ingredient mapping only. Drugvu is not affiliated with any manufacturer. This is not medical advice.
6 Fertility, pregnancy and lactation Physicians should carefully consider the potential risks and benefit for each specific patient before prescribing chlorhexidine. Chlorhexidine has been used in pregnant women and no harmful effects have been reported.
There are no adequate data to support the use of chlorhexidine in lactating women. 7 Effects on ability to drive and use machines Chlorhexidine acetate has no influence on the ability to drive and use machines.. 4 Special Warnings and Precautions for Use).
Reporting of suspected adverse reactions Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme.
uk/yellowcard
Serious cases of persistent corneal injury, potentially requiring corneal transplant, were reported following accidental ocular exposure to chlorhexidine containing medicinal products despite taking eye protective measures due to migration of solution beyond the intended surgical preparation area.
Extreme care must be taken during application to ensure that chlorhexidine does not migrate beyond its intended application site into the eyes. Particular care should be taken in anesthetized patients, who are unable to immediately report ocular exposure.
If chlorhexidine comes into contact with the eyes, wash out promptly and thoroughly with water. An ophthalmologist’s advice should be sought. 4 Warnings – Chemical Burns in Neonates).