CARE ST JOHNS WORT LOW MOOD RELIEF

For oral short term use only. For adults and the elderly, take 2 tablets once daily. The tablets should be swallowed whole with a little liquid. 4 ‘Special warnings and precautions for use’) A doctor or qualified healthcare practitioner should be consulted if symptoms worsen or do not improve after 6 weeks.

Gastrointestinal disorders including dyspepsia, anorexia, nausea, diarrhoea or constipation; allergic skin reactions such as rash, urticaria, pruritis; fatigue and restlessness have been reported. The frequency is not known. Fair-skinned individuals may react with intensified sunburn-like symptoms under intense sunlight or strong ultra-violet (UV) irradiation.

Other adverse reactions that have been reported include headaches, neuropathy, anxiety, dizziness and mania. If other adverse reactions not mentioned above occur a doctor or qualified healthcare practitioner should be consulted. Reporting of suspected adverse reactions Reporting suspected adverse reactions after authorisation of the medicinal product is important.

It allows continued monitoring of the benefit/risk balance of the medicinal product. uk/yellowcard or search for ‘MHRA Yellow Card’ in the Google Play or Apple App Store.

Do not exceed the stated dose. If the condition worsens, or if symptoms persist for more than six weeks medical advice should be sought. The use of this product in children or adolescents under 18 years of age is not recommended because data are not sufficient and medical advice should be sought.

This product is intended for relief of symptoms of slightly low mood and mild anxiety. Patients with signs and symptoms of depression should seek medical advice for appropriate treatment. In very rare cases, particularly in fair-skinned persons, sun burn type reactions on skin areas exposed to strong sunlight may occur due to photosensitisation by St John’s Wort.

Persons using this product should avoid excessive sunbathing or the use of sun-beds or solariums. 5).

Hypersensitivity to the active ingredient or any of the excipients. Patients with known dermal photosensitivity or patients undergoing phototherapy or any photodiagnostic procedures. 5 ‘Interactions with other medicinal products and other forms of interaction’).

This is because St John’s Wort (Hypericum perforatum) has been shown to induce the cytochrome P450 isoenzymes CYP1A2, CYP2C19, CYP2C9 and CYP3A4 as well as transport protein P-glycoprotein. This results in pharmacokinetic interactions with a large number of medicines including leading to a possible decrease in the effectiveness of those medicines.

In addition, pharmacodynamic interactions have also been identified with antidepressants, particularly the SSRI antidepressants and with the triptan group of medicines.