ATROPINE SULPHATE

Cardiopulmonary Resuscitation in Adults and Children over 12 years of age: 3mg Intravenous Injection once only. As an Antidote to Cholinesterase Inhibitors in Adults and Children over 12 years of age: 2mg intramuscular or Intravenous Injection, repeat dose every 5 - 10 minutes until signs of atropinisation appear.

As an Antidote to Organophosphate Pesticides and in Mushroom Poisoning in Adults and Children over 12 years of age: 2mg Intramuscular or Intravenous Injection, repeat dose every 10 - 30 minutes until muscarinic signs and symptoms subside.

Bradycardia associated with acute myocardial infarction in Adults and children over 12 years of age: 300 micrograms initially, increasing to 1mg if necessary Children under 12 years of age: Not recommended.

Elderly:

As for Adults

Side effects which are common include, dry mouth with difficulty in swallowing, difficulty with micturition and constipation, thirst, dilation of the pupils with loss of accommodation and photophobia, flushing, dryness of the skin, bradycardia followed by tachycardia, palpitations and arrhythmias, vomiting, fever, rashes and confusional states may occur especially in the elderly.

Reporting of suspected adverse reactions Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. uk/yellowcard.

Atropine Sulphate should be used with caution in children, the elderly and those with Down’s Syndrome. It should be given with caution to patients with diarrhoea, urinary retention, acute myocardial infarction, hypertension or fever, and when the ambient temperature is high.

Caution is also required when using the drug in patients with conditions characterised by tachycardia such as thyrotoxicosis, cardiac insufficiency or failure and during cardiac surgery.

Known hypersensitivity to atropine, closed angle glaucoma, prostatic enlargement, paralytic ileus or pyloric stenosis, myasthenia gravis, severe ulcerative colitis.