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TEVA-PREDNISONE is a brand name for Prednisone, supplied as a tablet. The medicine, its uses, side effects and dosage are the same regardless of brand.
Verbatim from this product's HC label. Tap a section to expand.
Note:
The following are typical for all systemic corticosteroids. Their inclusion in this list does not necessarily indicate that the specific event has been observed with this particular formulation.
Cardiac disorders:
Cardiac failure congestive (in susceptible patients); Bradycardia; Cardiac arrest; Arrhythmia; Cardiomegaly; Circulatory collapse; Fat embolism; Hypertrophic cardiomyopathy in premature infants; Myocardial rupture following recent myocardial infarction Pulmonary oedema; Syncope; Tachycardia; Embolism; Thrombophlebitis; Vasculitis.
Fluid and electrolyte disturbances: sodium retention; fluid retention; congestive heart failure in susceptible patients; potassium loss, hypokalemic alkalosis; hypertension. Musculoskeletal: steroid myopathy; muscle weakness; osteoporosis; pathologic fractures; vertebral compression fractures, aseptic necrosis.
Gastrointestinal: peptic ulcer with possible perforation and hemorrhage; gastric hemorrhage; pancreatitis; esophagitis; perforation of the bowel. Dermatologic: impaired wound healing; petechiae and ecchymoses; thin fragile skin. Metabolic: negative nitrogen balance due to protein catabolism.
Neurological: increased intracranial pressure; pseudotumor cerebri; psychic derangements and seizures. Endocrine: menstrual irregularities; development of Cushingoid state; suppression of pituitary-adrenal axis; decreased carbohydrate tolerance; manifestations of latent diabetes mellitus; increased requirements for insulin or oral hypoglycemic agents in diabetes; suppression of growth in children.
-11 Ophthalmic: posterior subcapsular cataracts; increased intraocular pressure; exophthalmos. Immune System: masking of infections; latent infections becoming active; opportunistic infections; hypersensitivity reactions including anaphylaxis; may suppress reactions to skin tests.
Other:
A steroid withdrawal syndrome seemingly unrelated to adrenocortical insufficiency and consistin g of anorexia, nausea and vomiting, lethargy, headache, fever, joint pain, desquamation, myalgia, weight loss and/or hypotension has been reported following abrupt withdrawal of glucocorticoids.
Symptoms often occurred while plasma glucocorticoid concentrations were still high but were falling rapidly; apparently the abrupt change in glucocorticoid concentration rather than a low concentration per se was responsible for the phenomenon.
(See DOSAGE AND ADMINISTRATION). html) for information on how to report online, by mail or by fax; or • Calling toll-free at 1-866-234-2345.
NOTE:
Contact your health professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice. DOSAGE AND ADMINISTRATION The initial dosage may vary from 5 to 60 mg of prednisone per day depending on the specific disease entity being treated.
Not medical advice. Always read the patient information leaflet and follow your prescriber or pharmacist.
Other brands of Prednisone in Canada.
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Brand names are compiled from public regulatory records for active-ingredient mapping only. Drugvu is not affiliated with any manufacturer. This is not medical advice.
In situations of less severity, lower doses will generally suffice while in selected patients higher initial doses may be required. The initial dosage should be maintained or adjusted until a satisfactory response is noted. If after a reasonable period of time there is a lack of satisfactory clinical response, prednisone should be discontinued.
It should be emphasized that dosage requirements are variable and must be -12 individualized on the basis of the disease under treatment and the response of the patient. After a favorable response is noted, the proper maintenance dosage should be determined by decreasing the initial drug dosage in small decrements at appropriate time intervals until the lowest dosage which will maintain an adequate clinical response is reached.
It should be kept in mind that constant monitoring is needed in regard to drug dosage. Included in the situations which may make dosage adjustments necessary are changes in clinical status secondary to remissions or exacerbations in the disease process, the patient's individual drug responsiveness, and the effect of patient exposure to stressful situations not directly related to the disease entity under treatment; in this latter situation it may be necessary to increase the dosage of prednisone for a period of time consistent with the patient's condition.
ADT-Alternate Day Therapy:
Alternate day therapy is a corticosteroid dosing regimen in which twice the usual daily dose of corticosteroid is administered every other morning. The purpose of this mode of therapy is to provide a patient requiring long-term, pharmacologic dose treatment with the beneficial effects of corticoids while minimizing certain undesirable effects, including pituitary-adrenal suppression, the Cushingoid state, corticoid withdrawal symptoms, and growth suppression in children.
Discontinuance of Therapy Although high-dose glucocorticoid therapy used for only brief periods in emergency situations may be reduced and discontinued quite rapidly, withdrawal following long-term therapy with pharmacologic dosages of systemic glucocorticoids should be very gradual until recovery of HPA- axis function occurs.
(See ACTION and CLINICAL PHARMACOLOGY). Many methods of slow withdrawal or "tapering" have been described. , 5 mg of -13 prednisone) is reached. 5 mg of prednisone (or its equivalent) every 1-2 weeks except in patients on alternate-day therapy in whom it may be possible to decrease dosage in decrements of 5 mg of prednisone at 1-to 2-week intervals.
If the disease flares up during withdrawal, dosage may need to be increased and followed by a more gradual withdrawal. In addition, […]