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SMOFKABIVEN PERIPHERAL is a brand name for Soybean Oil, supplied as a emulsion. The medicine, its uses, side effects and dosage are the same regardless of brand.
Used for: AND CLINICAL USE ..............................................................................3 CONTRAINDICATIONS ...................................................................................................4 WARNINGS AND PRECAUTIONS…
Verbatim from this product's HC label. Tap a section to expand.
g. severe post-traumatic conditions, uncompensated diabetes mellitus, acute myocardial infarction, stroke, embolism, metabolic acidosis, severe sepsis, hypotonic dehydration, and hyperosomolar coma) WARNINGS AND PRECAUTIONS General The infusion must be stopped immediately if any signs or symptoms of allergic reactions (such as fever, shivering, sweating, headache, skin rashes, or dyspnea) develop.
SmofKabiven Peripheral should be infused with caution in conditions of impaired lipid metabolism, which may occur in patients with renal failure, diabetes mellitus, pancreatitis, impaired liver function, hypothyroidism, and sepsis.
To avoid risks associated with too rapid delivery, it is recommended to use a continuous and well-controlled infusion, if possible a volumetric pump. g. abnormally high or low serum levels of the electrolytes) should be corrected before starting the infusion of SmofKabiven Peripheral.
SmofKabiven Peripheral should be given with caution to patients prone to retaining electrolytes. Special monitoring is required at the beginning of any intravenous infusion. Should any abnormal sign occur, the infusion must be stopped.
The amount of individual electrolytes to be added is determined by the clinical condition of the patient and by frequent monitoring of serum levels. Parenteral nutrition should be given with caution in metabolic acidosis, cellular hypoxia and increased serum osmolarity.
Page 5 of 58 Parenteral nutrition infusion may be accompanied by increased urinary excretion of the trace elements, in particular copper and zinc. This should be considered in the dosing of trace elements, especially during long-term parenteral nutrition.
Amounts of zinc present in SmofKabiven Peripheral should be taken into account. In malnourished patients, initiation of parenteral nutrition can precipitate fluid shifts resulting in pulmonary edema and congestive heart failure as well as a decrease in the serum concentration of potassium, phosphate, magnesium, and water soluble vitamins.
These changes can occur within 24 to 48 hours. Therefore, careful and slow initiation of parenteral nutrition is recommended in this patient group, together with close monitoring and appropriate adjustments of fluid, electrolytes, minerals, and vitamins.
Not medical advice. Always read the patient information leaflet and follow your prescriber or pharmacist.
Other brands of Soybean Oil in Canada.
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Brand names are compiled from public regulatory records for active-ingredient mapping only. Drugvu is not affiliated with any manufacturer. This is not medical advice.
SmofKabiven Peripheral must not be given simultaneously with transfusion blood in the same Y- on-site infusion set due to the risk of pseudoagglutination. Since an increased risk of infection is associated with the use of any central vein, strict aseptic precautions should be taken to avoid any contamination during catheter insertion and manipulation.
Fat overload syndrome is a rare condition that has been reported with intravenous lipid formulations. g. coma). The cause of the fat overload syndrome is unclear. The syndrome is usually reversible when the infusion of the lipid emulsion is stopped.
Although it has been most frequently observed when the recommended lipid dosage was exceeded, cases have also been described where the lipid formulation was administered according to instructions. Cardiovascular Fluid status should be closely monitored in patients with pulmonary edema or heart failure.
Endocrine and Metabolism In patients with hyperglycemia, administration of exogenous insulin might be necessary SmofKabiven Peripheral should be given with caution in conditions of impaired amino acid metabolism and of impaired lipid metabolism, which may occur in patients with renal failure, diabetes mellitus, pancreatitis, impaired liver function, hypothyroidism, and sepsis.
g. hemoglobin. Page 6 of 58 Immune This intravenous emulsion contains soybean oil, fish oil and egg phospholipids which may rarely cause allergic reactions. Allergic cross reaction has been observed between soybean and peanut oil. If a hypersensitivity reaction occurs (signs or symptoms of anaphylactic reaction such as fever, shivering, sweating, headache, skin rash, or dyspnoea) infusion of the emulsion must be stopped immediately and the appropriate treatment and supportive measures should be undertaken until the conditions have been resolved.
Renal Use with caution in patients with renal insufficiency. g. hyperphosphatemia and hyperkalemia. Fluid and electrolyte status should be closely monitored in these patients.
Special Populations Pregnant Women:
There are no data available on exposure of SmofKabiven Peripheral in pregnant women. There are no studies available on reproductive toxicity in animals. Parenteral nutrition may become necessary during pregnancy. Then SmofKabiven Peripheral should only be given to pregnant women after physicians have […]