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RBX-RAMIPRIL is a brand name for Ramipril, supplied as a capsule. The medicine, its uses, side effects and dosage are the same regardless of brand.
Used for: AND CLINICAL USE ..............................................................................3 CONTRAINDICATIONS ...................................................................................................4 ADVERSE…
Verbatim from this product's HC label. Tap a section to expand.
Patients who are hypersensitive to this drug, any other angiotensin converting enzyme (ACE) inhibitor, or to any ingredient in the formulation or component of the container. For a complete listing of ingredients see Dosage Forms, Composition and Packaging section of the product monograph.
Patients who have a history of hereditary/idiopathic angioedema, or angioedema with or without treatment with an ACE inhibitor Pregnant and nursing women (see Warnings and Precautions, Special Populations, Pregnant Women and Nursing Women) Patients with hemodynamically relevant bilateral renal artery stenosis, or unilateral in the single kidney (see WARNINGS AND PRECAUTIONS, Renal, Renal impairment).
Patients with hypotensive states or hemodynamically unstable states. Concomitant use with sacubitril/valsartan due to an increased risk of angioedema. Do not initiate RBX-RAMIPRIL until at least 36 hours have elapsed following the last dose of sacubitril/valsartan.
In the case of a switch from RBX-RAMIPRIL to sacubitril/valsartan, do not start sacubitril/valsartan until at least 36 hours have elapsed following the last dose of RBX-RAMIPRIL. 73m2) o hyperkalemia (> 5 mMol/L) o congestive heart failure who are hypotensive [see WARNINGS and PRECAUTIONS, Dual Blockade of the Renin-Angiotensin System (RAS) and Renal, and DRUG INTERACTIONS, Dual Blockade of the Renin- Angiotensin System (RAS)].
73m2) o hyperkalemia (> 5 mMol/L) o congestive heart failure who are hypotensive [see WARNINGS and PRECAUTIONS, Dual Blockade of the Renin-Angiotensin System (RAS) and Renal, and DRUG INTERACTIONS, Dual Blockade of the Renin- Angiotensin System (RAS)].
Combination with extracorporeal treatments leading to contact of blood with negatively charged surfaces since such use may lead to anaphylactoid reactions. g. polyacrylonitril) membranes and low-density lipoprotein apheresis with dextran sulfate (see WARNINGS AND PRECAUTIONS, Immune).
WARNINGS AND PRECAUTIONS Serious Warnings and Precautions When used in pregnancy, angiotensin converting enzyme (ACE) inhibitors can cause injury PrRBX™-RAMIPRIL (Ramipril Capsules, Mfr. ) Product Monograph Page 5 of 38 or even death of the developing fetus.
When pregnancy is detected RBX-RAMIPRIL should be discontinued as soon as possible (see WARNINGS AND PRECAUTIONS, Special Populations, Pregnant Women). General Cough A dry, persistent cough, which usually disappears only after withdrawal or lowering of the dose of ramipril, has been reported.
Not medical advice. Always read the patient information leaflet and follow your prescriber or pharmacist.
Other brands of Ramipril in Canada.
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Brand names are compiled from public regulatory records for active-ingredient mapping only. Drugvu is not affiliated with any manufacturer. This is not medical advice.
Such possibility should be considered as part of the differential diagnosis of cough (see ADVERSE REACTIONS). g. g. operating a vehicle or machinery). 73m2). Therefore, the use of ramipril in combination with aliskiren-containing drugs is contraindicated in these patients (see CONTRAINDICATIONS).
The use of RBX-RAMIPRIL in combination with an ARB is contraindicated in patients with diabetic nephropathy (see CONTRAINDICATIONS). Further, co-administration of ACE inhibitors, including RBX-RAMIPRIL, with other agents blocking the RAS, such as ARBs or aliskiren-containing drugs, is generally not recommended in other patients, since such treatment has been associated with an increased incidence of severe hypotension, renal failure, and hyperkalemia (see DRUG INTERACTIONS).
Cardiovascular Aortic Stenosis There is concern, on theoretical grounds, that patients with aortic stenosis might be at particular risk of decreased coronary perfusion when treated with vasodilators because they do not develop as much afterload reduction.
Hypotension Symptomatic hypotension has occurred after administration of ramipril, usually after the first or second dose or when the dose was increased. , stenosis of the aortic valve) or in patients with hemodynamically relevant renal artery stenosis.
All patients should be cautioned about this potential excessive fall in BP and advised to consult their physician. PrRBX™-RAMIPRIL (Ramipril Capsules, Mfr. ) Product Monograph Page 6 of 38 Generally, it is recommended that dehydration, hypovolaemia or salt depletion be corrected before initiating treatment (in patients with heart failure, however, such corrective action must be carefully weighed against the risk of volume overload).
When these conditions have become clinically relevant, treatment with ramipril must only be started or continued if appropriate steps are taken concurrently to prevent an excessive fall in BP and deterioration of renal function. In […]