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PRUCALOPRIDE is a brand name for Prucalopride, supplied as a tablet. The medicine, its uses, side effects and dosage are the same regardless of brand.
Used for: AND CLINICAL USE .......................................................................................... 3 CONTRAINDICATIONS ................................................................................................................ 3 WARNINGS AND PRECAUTIONS…
Verbatim from this product's HC label. Tap a section to expand.
Dosing Considerations • Due to the specific mode of action of PRUCALOPRIDE (stimulation of propulsive motility), exceeding the daily dose of 2 mg is not expected to increase efficacy. • If the intake of once daily PRUCALOPRIDE is not effective during the first 4 weeks of treatment, therapy should be discontinued.
• The efficacy of prucalopride has been established in double-blind, placebo-controlled studies for up to 3 months. In case of prolonged treatment the benefit should be re- assessed at regular intervals. Recommended Dose and Dosage Adjustment Adults: 2 mg once daily.
, rescue treatment) during the ongoing PRUCALOPRIDE treatment. Elderly (>65 years): 1 mg tablet once daily (see ACTION AND CLINICAL PHARMACOLOGY, Pharmacokinetics); if needed the dose can be increased to 2 mg once daily.
Children (<18 years):
PRUCALOPRIDE is not recommended in children younger than 18 years old (see ACTION AND CLINICAL PHARMACOLOGY, Pharmacokinetics). 73 m2) is 1 mg once daily (see CONTRAINDICATIONS and Pharmacokinetics). No dose adjustment is required for patients with mild to moderate renal impairment.
Patients with hepatic impairment:
Patients with severe hepatic impairment (Child-Pugh class C) start with 1 mg once daily which may be increased to 2 mg if required to improve efficacy and if the 1 mg dose is well tolerated (see WARNINGS AND PRECAUTIONS and ACTION AND CLINICAL PHARMACOLOGY, Special Populations and Conditions).
No dose adjustment is required for patients with mild to moderate hepatic impairment. Missed Dose Prucalopride has a terminal half-life of approximately 1 day. The dose should not be doubled to make up for a missed dose. Administration PRUCALOPRIDE film-coated tablets are for oral use and can be taken with or without food, at any time of the day.
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Not medical advice. Always read the patient information leaflet and follow your prescriber or pharmacist.
Other brands of Prucalopride in Canada.
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Brand names are compiled from public regulatory records for active-ingredient mapping only. Drugvu is not affiliated with any manufacturer. This is not medical advice.