Loading…
NB-RISPERIDONE is a brand name for Risperidone, supplied as a tablet. The medicine, its uses, side effects and dosage are the same regardless of brand.
Used for: AND CLINICAL USE ............................................................................. 3 CONTRAINDICATIONS................................................................................................... 4 WARNINGS AND PRECAUTIONS…
Verbatim from this product's HC label. Tap a section to expand.
). Discontinuation should be considered if signs and symptoms of cerebrovascular adverse events occur. d. is recommended. 25 mg per day approximately every 2 to 4 days. d. 0 mg per day) for most patients. d. 0 mg per day). Periodic dosage adjustments (increase or decrease) or discontinuation of treatment should be considered because of the instability of the symptoms treated.
Since there is no experience in younger patients, dosage recommendations cannot be made.
Bipolar Mania:
NB-Risperidone should be administered on a once-daily schedule, starting with 2 mg to 3 mg per day. Dosage adjustments, based on clinical response and tolerability, should occur at intervals of not less than 24 hours and in dosage increments or decrements of 1 mg per day.
Risperidone doses higher than 6 mg per day were not studied in patients with bipolar disorder. In two controlled trials, the most common daily dose was 1-4 mg/day. In each of the three controlled trials, risperidone was effective across the dose range used, although the effect size in the 3-4 mg/day mean modal dose group was larger than in the 5-6 mg/day mean modal dose group (mean modal dose is the average of the most frequent daily dose across the three trials).
The safety and effectiveness of risperidone for long-term use and for prophylactic use in bipolar disorder have not been evaluated. Physicians who elect to use NB-Risperidone for extended periods should periodically re-evaluate the long-term risks and benefits of the drug for the individual patient.
Special Populations Geriatrics:
Risperidone is substantially excreted by the kidneys. Thus, the risk of toxic reactions to this drug may be greater in patients with impaired renal function. Because elderly patients are more likely to have decreased renal function, caution should be taken in dose selection and titration.
9). d. starting dose to a maximum daily dose of 3 mg. 9). d. should be considered.
Patients with Impaired Liver Function:
NB-Risperidone should be used with caution in patients with hepatic impairment. Patients with impaired hepatic function have increases in plasma concentration of the free fraction of risperidone and this may result in an enhanced effect.
Not medical advice. Always read the patient information leaflet and follow your prescriber or pharmacist.
Other brands of Risperidone in Canada.
Know a brand we are missing in Canada? Suggest a brand →
Brand names are compiled from public regulatory records for active-ingredient mapping only. Drugvu is not affiliated with any manufacturer. This is not medical advice.
d. schedule. d. d. d. d. 9).
Patients with Impaired Kidney Function:
NB-Risperidone should be used with caution in patients with renal impairment. Patients with renal impairment have less ability to eliminate the active antipsychotic fraction than normal adults. d. schedule. d. d. d. should generally occur at intervals of at least 1 week.
9). Missed Dose The missed dose should be taken at the next scheduled dose. Doses should not be doubled. Administration NB-Risperidone is given as tablets. NB-Risperidone may be taken with or without meals. In order to avoid orthostatic hypotension, the dose of NB-Risperidone should be adjusted gradually.
OVERDOSAGE For management of a suspected drug overdose, contact your regional Poison Control Centre. Cases of overdose have been reported with risperidone; the estimated doses were between 20 and 360 mg. In general, reported signs and symptoms were those resulting from an exaggeration of the drug’s known pharmacological effects, namely drowsiness, sedation, tachycardia, NB-Risperidone Page 34 of 64 hypotension and extrapyramidal symptoms.
In overdose, QT-prolongation, widened QRS complex, convulsions, hyponatremia and hypokalemia were also reported. Torsades de pointes has been reported in association with combined overdose of oral risperidone and paroxetine. Treatment of Overdosage Since there is no specific antidote to risperidone, treatment is primarily supportive.
A patent airway must be established and maintained to ensure adequate ventilation and oxygenation. Administration of activated charcoal together with a laxative should be considered. Cardiovascular monitoring should commence immediately and should include continuous electrocardiographic monitoring to detect possible arrhythmias.
[…]