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IMIPENEM AND CILASTATIN FOR is a brand name for Imipenem, supplied as a powder for solution. The medicine, its uses, side effects and dosage are the same regardless of brand.
Used for: Imipenem and Cilastatin for Injection USP is indicated for: Imipenem and Cilastatin for Injection USP may be indicated in the treatment of serious infections when caused by sensitive strains of bacteria. Where considered necessary, therapy may be initiated on the basis of clinical judgment before results of…
Verbatim from this product's HC label. Tap a section to expand.
1 Dosing Considerations 07/2022 4 DOSAGE AND ADMINISTRATION 07/2022 7 WARNINGS AND PRECAUTIONS 07/2022 TABLE OF CONTENTS Se cti ons or subsecti ons that are not appl i cabl e at the ti me of authori zati on are not l i sted. RECENT MAJOR LABEL CHANGES.............................................................................................
2 TABLE OF CONTENTS ............................................................................................................... 2 PART I: HEALTH PROFESSIONAL INFORMATION ......................................................................
4 1 INDICATIONS ................................................................................................................... 1 Pediatrics ...............................................................................................................
2 Geriatrics ............................................................................................................... 5 2 CONTRAINDICATIONS......................................................................................................
6 3 SERIOUS WARNINGS AND PRECAUTIONS BOX ................................................................. 6 4 DOSAGE AND ADMINISTRATION ..................................................................................... 1 Dosing Considerations............................................................................................
2 Recommended Dose and Dosage Adjustment ........................................................ 3 Reconsititution ...................................................................................................... 10
). Case reports in the literature have shown that co-administration of carbapenems, including imipenem, to patients receiving valproic acid or divalproex sodium results in a reduction in serum valproic acid concentrations. The valproic acid concentrations may drop below the therapeutic range as a result of this interaction.
In some cases of co-administration of imipenem with valproic acid, breakthrough seizures have occurred. Increasing the dose of valproic acid or divalproex sodium may not be sufficient to overcome this interaction. The concomitant use of imipenem and valproic acid/divalproex sodium is generally not recommended.
Anti-bacterials other than carbapenems should be considered to treat infections in patients whose seizures are well controlled on valproic acid or divalproex sodium. If administration of Imipenem and Cilastatin for Injection USP is necessary, supplemental anti- convulsant therapy should be considered (see
07/2022 TABLE OF CONTENTS Se cti ons or subsecti ons that are not appl i cabl e at the ti me of authori zati on are not l i sted. RECENT MAJOR LABEL CHANGES.............................................................................................
2 TABLE OF CONTENTS ............................................................................................................... 2 PART I: HEALTH PROFESSIONAL INFORMATION ......................................................................
4 1 INDICATIONS ................................................................................................................... 1 Pediatrics ...............................................................................................................
2 Geriatrics ............................................................................................................... 5 2 CONTRAINDICATIONS......................................................................................................
6 3 SERIOUS WARNINGS AND PRECAUTIONS BOX ................................................................. 6 4 DOSAGE AND ADMINISTRATION ..................................................................................... 1 Dosing Considerations............................................................................................
2 Recommended Dose and Dosage Adjustment ........................................................ 3 Reconsititution ...................................................................................................... 40 17 SUPPORTING PRODUCT MONOGRAPHS […]
IMIPENEM AND CILASTATIN FOR INJECTION USP IS CONTRAINDICATED IN PATIENTS WHO ARE HYPERSENSITIVE TO THIS DRUG OR TO ANY INGREDIENT IN THE FORMULATION, INCLUDING ANY NON-MEDICINAL INGREDIENT, OR COMPONENT OF THE CONTAINER. FOR A COMPLETE LISTING, SEE 6 DOSAGE FORMS, STRENGTHS, COMPOSITION AND PACKAGING.
Not medical advice. Always read the patient information leaflet and follow your prescriber or pharmacist.
Other brands of Imipenem in Canada.
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