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FENTANYL CITRATE is a brand name for Fentanyl, supplied as a solution. The medicine, its uses, side effects and dosage are the same regardless of brand.
Used for: AND CLINICAL USE ..............................................................................3 CONTRAINDICATIONS....................................................................................................4 WARNINGS AND PRECAUTIONS…
Verbatim from this product's HC label. Tap a section to expand.
SERIOUS WARNINGS AND PRECAUTIONS
, non-opioid analgesics) are ineffective, not tolerated, or would be otherwise inadequate to provide appropriate management of pain (see DOSAGE AND ADMINISTRATION). As with other CNS depressants, patients who have received fentanyl should have appropriate surveillance.
Resuscitative equipment and a narcotic antagonist such as naloxone should be readily available to manage apnea. Addiction, Abuse, and Misuse Fentanyl Citrate Injection poses risks of opioid addiction, abuse, and misuse, which can lead to overdose and death.
Each patient’s risk should be assessed prior to prescribing Fentanyl Citrate Injection and all patients should be monitored regularly for the development of these behaviours or conditions (see WARNINGS AND PRECAUTIONS, Abuse and Misuse).
Fentanyl Citrate Injection should be stored securely to avoid theft or misuse.
Life-threatening Respiratory Depression:
OVERDOSE Serious, life-threatening, or fatal respiratory depression may occur with use of Fentanyl Citrate Injection. Infants exposed in-utero or through breast milk are at risk of life- threatening respiratory depression upon delivery or when nursed.
Patients should be monitored for respiratory depression, especially during initiation of Fentanyl Citrate Injection or following a dose increase. Further, instruct patients of the hazards related to taking opioids including fatal overdose.
Accidental Exposure Accidental exposure of even one dose of Fentanyl Citrate Injection, especially by children, can result in a fatal overdose of fentanyl (see DOSAGE AND ADMINISTRATION, Disposal, for instructions on proper disposal).
Neonatal Opioid Withdrawal Syndrome Prolonged maternal use of Fentanyl Citrate Injection during pregnancy can result in neonatal opioid withdrawal syndrome, which may be life-threatening (see WARNINGS AND PRECAUTIONS, Neonatal Opioid Withdrawal Syndrome (NOWS)).
Fentanyl Citrate Injection. Page 6 of 45 General Fentanyl Citrate Injection should be stored securely to avoid theft or misuse. Fentanyl Citrate Injection should only be prescribed by persons knowledgeable in the continuous administration of potent opioids, in the management of patients receiving potent opioids for the treatment of pain, and in the detection and management of respiratory depression, including the use of opioid antagonists.
Not medical advice. Always read the patient information leaflet and follow your prescriber or pharmacist.
Other brands of Fentanyl in Canada.
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Brand names are compiled from public regulatory records for active-ingredient mapping only. Drugvu is not affiliated with any manufacturer. This is not medical advice.
If fentanyl is administered with a tranquilizer such as droperidol, the user should familiarize himself with the special properties of each drug, particularly the widely differing durations of action. In addition, when such a combination is used, fluids and other countermeasures to manage hypotension should be available (see DRUG INTERACTIONS).
Patients should be cautioned not to consume alcohol while taking Fentanyl Citrate Injection as it may increase the chance of experiencing serious adverse events, including death. Hyperalgesia that will not respond to a further dose increase of fentanyl can occur at particularly high doses.
A fentanyl dose reduction or change in opioid may be required. Abuse and Misuse Like all opioids, Fentanyl Citrate Injection is a potential drug of abuse and misuse, which can lead to overdose and death. Therefore, Fentanyl Citrate Injection should be prescribed and handled with caution.
Patients should be assessed for their clinical risks for opioid abuse or addiction prior to being prescribed opioids. All patients receiving opioids should be routinely monitored for signs of misuse and abuse. Interaction with Alcohol The co-ingestion of alcohol with Fentanyl Citrate Injection should be avoided as it may result in dangerous additive effects, causing serious injury or death (see WARNINGS AND PRECAUTIONS, General, and DRUG INTERACTIONS, Drug-Lifestyle Interactions).
Risks From Concomitant Use With Benzodiazepines Or Other CNS Depressants Concomitant use of opioids with benzodiazepines or other central nervous system (CNS) depressants, including alcohol, may result in profound sedation, respiratory depression, coma, and death (see WARNINGS AND PRECAUTIONS, Neurologic and DRUG INTERACTIONS).
Reserve concomitant prescribing of Fentanyl Citrate Injection and benzodiazepines or other CNS depressants for use in patients for whom alternative treatment options are inadequate. Limit dosages and durations to the minimum required.
Follow patients for signs and symptoms of respiratory depression and sedation. Fentanyl Citrate Injection. Page 7 of 45 Opioids, such as Fentanyl Citrate Injection, should be used with particular care in patients with a history of alcohol and illicit/prescription drug abuse.
However, concerns about abuse, addiction, and diversion should not prevent the proper management of pain. Cardiovascular Fentanyl administration may result in severe hypotension in patients whose ability to maintain adequate blood pressure is compromised by reduced blood volume, or concurrent administration of drugs such as phenothiazines and other tranquilizers, sedative/hypnotics, tricyclic antidepressants or general anesthetics.
These patients should be monitored for signs of hypotension after initiating or titrating the dose of Fentanyl Citrate Injection. The use of Fentanyl Citrate Injection in patients with circulatory shock should be avoided as it may cause vasodilation that can further reduce cardiac output and blood pressure.
Rapid intravenous injection of opioid analgesics increases the possibility of hypotension and respiratory depression and should be avoided (see DOSAGE AND ADMINISTRATION). Vital signs should be monitored routinely. Fentanyl may produce bradycardia, which may be treated with atropine; however, fentanyl should be used with caution in […]