ADVIL EXTRA STRENGTH

Serious Warnings and Precautions • Caution in those with heart failure, high blood pressure or other conditions that may cause excess fluid collecting in tissues. • Caution in patients at risk of gastrointestinal tract irritation, including those with a history of peptic ulcer.

The chance of stomach bleeding is higher if you are: age 60 or older, have had stomach ulcers or bleeding problems, take a blood thinner or steroid drug, take with other drugs containing an NSAID like acetylsalicylic acid (ASA), ibuprofen, naproxen, or prescription anti- inflammatory drugs, have 3 or more alcoholic drinks every day while using this product.

• Caution in patients at risk of kidney problems, including the elderly or those using diuretics. • Stop use immediately if you have difficulty or pain when urinating. • Advil Tablets should not be used during third trimester of pregnancy.

• Talk to your doctor if you are trying to conceive, in your first or second trimester of pregnancy or if breastfeeding BEFORE you use Advil Tablets talk to your doctor or pharmacist if:  you have previous or current stomach ulcers, diabetes, high blood pressure, heart failure, heart disease or thyroid disease, asthma, kidney or liver disease, glaucoma, blood clotting disorder (such as hemophilia), any other serious disease, are under doctor’s care for any serious condition, you are trying to conceive, pregnant or breastfeeding or are taking any other drug including over the counter drugs.

Use with caution in the elderly. Long-term continuous use may increase the risk of heart attack or stroke. The use of NSAIDs, like Advil Tablets, in the second trimester of pregnancy should be restricted to the lowest dose necessary for the shortest possible duration.

At 20 weeks or later in pregnancy, your use of NSAIDs may need to be monitored by a doctor due to the rare risk of kidney problems in the unborn baby which may result in decreased amniotic fluid volume and other complications. Stop use and ask a doctor if • you show signs of stomach bleeding • pain worsens or lasts more than 5 days • fever worsens or lasts more than 3 days • any new symptoms appear INTERACTIONS WITH THIS MEDICATION Do not use this product if you are taking: • Daily low dose ASA (81 – 325 mg), without talking to a doctor or pharmacist.

Ibuprofen may interfere with the preventive benefits of ASA. • ASA or other anti-inflammatory medication. Talk to your doctor or pharmacist if you are taking other medication (prescription or non-prescription) such as any of the following (NOT a complete list): acetaminophen, anticoagulants (blood thinners), digoxin, oral antidiabetic agents and insulin, diuretics, methotrexate, lithium, protein-bound drugs including probenecid, thyroxine, antibiotics, cyclosporine, phenytoin, corticosteroids or benzodiazepines, other NSAIDs, or medications for high blood pressure.