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ACT QUETIAPINE is a brand name for Quetiapine, supplied as a tablet. The medicine, its uses, side effects and dosage are the same regardless of brand.
Verbatim from this product's HC label. Tap a section to expand.
). , dehydration, hypovolemia and treatment with antihypertensive medications) (see
). 4% (2/527) on active control drugs. The risk of hypotension and syncope may be reduced by more gradual titration to the target dose (see 4 DOSAGE AND ADMINISTRATION). , dehydration, hypovolemia and treatment with antihypertensive medications) (see 5 OVERDOSAGE).
QT Prolongation:
In clinical trials, quetiapine was not associated with a persistent increase in absolute QT intervals. However, the QT effect was not systematically evaluated in a thorough QT study. In post-marketing experience, there have been cases reported of QT prolongation at therapeutic doses in patients with concomitant illness and in patients taking medicines known to cause electrolyte imbalance or increase QT interval, and with overdose (see 5 OVERDOSAGE).
As with other antipsychotics, caution should be exercised when quetiapine is prescribed in patients with cardiovascular disease or family history of QT prolongation. , the elderly, patients with congenital long QT syndrome, congestive heart failure, heart hypertrophy, hypokalemia, or hypomagnesemia (see
Musculoskeletal - Rhabdomyolysis 01/2022 7 WARNINGS AND PRECAUTIONS - Psychiatric 01/2022 7 WARNINGS AND PRECAUTIONS - Skin 01/2022 TABLE OF CONTENTS Sections or subsections that are not applicable at the time of authorization are not listed PART I: HEALTH PROFESSIONAL INFORMATION........................................................................
4 1. INDICATIONS .................................................................................................................... 1 Pediatrics ....................................................................................................................
2 Geriatrics..................................................................................................................... 4 2. CONTRAINDICATIONS .......................................................................................................
5 3. SERIOUS WARNINGS AND PRECAUTIONS BOX .................................................................. 5 4. DOSAGE AND ADMINISTRATION....................................................................................... 1 Dosing Considerations ................................................................................................
2 Recommended Dose and Dosage Adjustment.............................................................. 4 Administration............................................................................................................ 5 Missed Dose ................................................................................................................
7 5. OVERDOSAGE ................................................................................................................... 8 6 DOSAGE FORMS, STRENGTHS, COMPOSITION AND PACKAGING ..................................... 10 7. WARNINGS AND PRECAUTIONS ......................................................................................
Not medical advice. Always read the patient information leaflet and follow your prescriber or pharmacist.
Other brands of Quetiapine in Canada.
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Brand names are compiled from public regulatory records for active-ingredient mapping only. Drugvu is not affiliated with any manufacturer. This is not medical advice.
1 Special Populations.................................................................................................... 1 Pregnant Women....................................................................................................
2 Breast-feeding ........................................................................................................ 3 Pediatrics................................................................................................................
4 Geriatrics ................................................................................................................ 23 8. ADVERSE REACTIONS ......................................................................................................
1 Adverse Reaction Overview ....................................................................................... 2 Clinical Trial Adverse Drug Reactions .......................................................................... 1 Clinical Trial Adverse Reactions – Pediatrics.............................................................
3 Less Common Clinical Trial Adverse Reactions ............................................................ 4 Abnormal Laboratory Findings: Hematologic, Clinical Chemistry and Other ................. 37 Quantitative Data ............................................................................................................
5 Post-Market Adverse Reactions.................................................................................. 39 9. DRUG INTERACTIONS......................................................................................................
2 Drug Interactions Overview........................................................................................ 3 Drug-Behavioural Interactions....................................................................................
4 Drug-Drug Interactions .............................................................................................. 5 Drug-Food Interactions ..............................................................................................
6 Drug-Herb Interactions .............................................................................................. 7 Drug-Laboratory Interactions .....................................................................................
43 ACT QUETIAPINE (Quetiapine Fumarate Immediate-Release Tablets) 25 mg, 100 mg, 150 mg, 200 mg & 300 mg Page 3 of 69 10. CLINICAL PHARMACOLOGY .............................................................................................
1 Mechanism of Action ............................................................................................... 2. Pharmacodynamics.................................................................................................
3 Pharmacokinetics .................................................................................................... 45 11. STORAGE, STABILITY AND DISPOSAL ...............................................................................
47 12. SPECIAL HANDLING INSTRUCTIONS................................................................................. 47 13. PHARMACEUTICAL INFORMATION.................................................................................. 48 14.
CLINICAL TRIALS.............................................................................................................. 1 Clinical Trials by Indication .......................................................................................
3 Comparative Bioavailability Study ............................................................................ 50 15. MICROBOLOGY ...............................................................................................................
51 16. NON-CLINICAL TOXICOLOGY ........................................................................................... 51 […]